Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data

M K A Basra; M S Salek; L Camilleri; R Sturkey; A Y Finlay

doi:10.1159/000365390

Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data

M K A Basra
, M S Salek
, L Camilleri
, R Sturkey
, A Y Finlay

Research output: Contribution to journal › Article › peer-review

403 Citations (Scopus)

Abstract

AIMS: To determine the minimal clinically important difference (MCID) of the Dermatology Life Quality Index (DLQI) and its responsiveness to change in inflammatory skin diseases.

METHODS: A longitudinal study: at stage 1, patients completed the DLQI and a disease severity global question; at stage 2, a global rating of change in quality of life (QoL; Global Rating of Change Questionnaire, GRCQ) was added and used as an anchor to measure the MCID of the DLQI.

RESULTS: 192 patients completed stage 1 and 107 completed stage 2. The mean DLQI score at stage 1 was 9.8 and 7.4 at stage 2 with a mean change of 2.4 (p < 0.0001). 31 patients experienced a 'small change' in their QoL (±3 and ±2) on the GRCQ. The mean corresponding change in DLQI scores was 3.3, which is regarded as the approximate MCID.

CONCLUSIONS: Previous estimates of the MCID of the DLQI have varied from 3 to 5. Although this study demonstrated a MCID of 3.3, we recommend that the MCID in inflammatory skin diseases should be 4.

Original language	English
Pages (from-to)	27-33
Number of pages	7
Journal	Dermatology in Practice
Volume	230
Issue number	1
Early online date	20 Jan 2015
DOIs	https://doi.org/10.1159/000365390
Publication status	E-pub ahead of print - 20 Jan 2015

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Dermatology
Female
Humans
Longitudinal Studies
Male
Middle Aged
Quality of Life
Skin Diseases
Surveys and Questionnaires
Young Adult

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10.1159/000365390

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title = "Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data",

abstract = "AIMS: To determine the minimal clinically important difference (MCID) of the Dermatology Life Quality Index (DLQI) and its responsiveness to change in inflammatory skin diseases.METHODS: A longitudinal study: at stage 1, patients completed the DLQI and a disease severity global question; at stage 2, a global rating of change in quality of life (QoL; Global Rating of Change Questionnaire, GRCQ) was added and used as an anchor to measure the MCID of the DLQI.RESULTS: 192 patients completed stage 1 and 107 completed stage 2. The mean DLQI score at stage 1 was 9.8 and 7.4 at stage 2 with a mean change of 2.4 (p < 0.0001). 31 patients experienced a 'small change' in their QoL (±3 and ±2) on the GRCQ. The mean corresponding change in DLQI scores was 3.3, which is regarded as the approximate MCID.CONCLUSIONS: Previous estimates of the MCID of the DLQI have varied from 3 to 5. Although this study demonstrated a MCID of 3.3, we recommend that the MCID in inflammatory skin diseases should be 4.",

keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Dermatology, Female, Humans, Longitudinal Studies, Male, Middle Aged, Quality of Life, Skin Diseases, Surveys and Questionnaires, Young Adult",

author = "Basra, \{M K A\} and Salek, \{M S\} and L Camilleri and R Sturkey and Finlay, \{A Y\}",

note = "{\textcopyright} 2015 S. Karger AG, Basel.",

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doi = "10.1159/000365390",

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AU - Basra, M K A

AU - Salek, M S

AU - Camilleri, L

AU - Sturkey, R

AU - Finlay, A Y

PY - 2015/1/20

Y1 - 2015/1/20

N2 - AIMS: To determine the minimal clinically important difference (MCID) of the Dermatology Life Quality Index (DLQI) and its responsiveness to change in inflammatory skin diseases.METHODS: A longitudinal study: at stage 1, patients completed the DLQI and a disease severity global question; at stage 2, a global rating of change in quality of life (QoL; Global Rating of Change Questionnaire, GRCQ) was added and used as an anchor to measure the MCID of the DLQI.RESULTS: 192 patients completed stage 1 and 107 completed stage 2. The mean DLQI score at stage 1 was 9.8 and 7.4 at stage 2 with a mean change of 2.4 (p < 0.0001). 31 patients experienced a 'small change' in their QoL (±3 and ±2) on the GRCQ. The mean corresponding change in DLQI scores was 3.3, which is regarded as the approximate MCID.CONCLUSIONS: Previous estimates of the MCID of the DLQI have varied from 3 to 5. Although this study demonstrated a MCID of 3.3, we recommend that the MCID in inflammatory skin diseases should be 4.

AB - AIMS: To determine the minimal clinically important difference (MCID) of the Dermatology Life Quality Index (DLQI) and its responsiveness to change in inflammatory skin diseases.METHODS: A longitudinal study: at stage 1, patients completed the DLQI and a disease severity global question; at stage 2, a global rating of change in quality of life (QoL; Global Rating of Change Questionnaire, GRCQ) was added and used as an anchor to measure the MCID of the DLQI.RESULTS: 192 patients completed stage 1 and 107 completed stage 2. The mean DLQI score at stage 1 was 9.8 and 7.4 at stage 2 with a mean change of 2.4 (p < 0.0001). 31 patients experienced a 'small change' in their QoL (±3 and ±2) on the GRCQ. The mean corresponding change in DLQI scores was 3.3, which is regarded as the approximate MCID.CONCLUSIONS: Previous estimates of the MCID of the DLQI have varied from 3 to 5. Although this study demonstrated a MCID of 3.3, we recommend that the MCID in inflammatory skin diseases should be 4.

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KW - Middle Aged

KW - Quality of Life

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KW - Surveys and Questionnaires

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Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data

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Keywords

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