Developmental evolution of dendritic morphology in a multi-compartmental neuron model

A.G. Rust, R.G. Adams

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)
30 Downloads (Pure)


Through the use of a multi-compartmental neuron simulation, Mainen and Sejnowski demonstrated that spike generation in neurons is a function of their dendritic structure [l]. In this paper we investigate the determination of dendritic morphology given a desired set of spike traces. A genetic algorithm is used to identify optimal parameters for a developmental model which simulates the growth of 3-dimensional dendrites. For two ’classes of ’neurons with different spiking behaviour, the developmental evolutionary process discovers ranges of viable dendritic morphologies which satisfactorally match the desired spike traces.
Original languageEnglish
Title of host publicationArtificial Neural Networks
Publication statusPublished - 1999


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