Evaluation of layers of the rat airway epithelial cell line RL-65 for permeability screening of inhaled drug candidates.

Keyphrases

• Inhaled Drugs 100%
• Epithelial Cell Line 100%
• Permeability Screening 100%
• Drug Candidates 100%
• Airway Epithelial Cells 100%
• Cell Layer 66%
• Drug Permeation 66%
• Liquid Cell 33%
• Vector Transport 33%
• Air-liquid Interface 33%
• Pulmonary Absorption 33%
• Epithelial Barrier 33%
• Cell Culture Model 33%
• Transwell Insert 33%
• Species Differences 33%
• Permeability Measurement 33%
• Epithelial Cell Culture 33%
• Immunohistochemistry 33%
• In Vitro Screening 33%
• Human Bronchial Epithelial 33%
• Rhodamine 123 33%
• Mannitol 33%
• Barrier Properties 33%
• Measuring Instrument 33%
• Respiratory Epithelial Cells 33%
• Preclinical Development 33%
• Bronchiolar Epithelium 33%
• P-glycoprotein (P-gp) 33%
• Epithelial Absorption 33%
• Drug Pharmacokinetics 33%
• In Vivo Prediction 33%
• Screening Tool 33%
• Absorption Model 33%
• Interface Layer 33%
• Digoxin 33%
• Serum-free Medium 33%
• Gene Analysis 33%
• Transepithelial Electrical Resistance 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Digoxin 100%
• Cell Culture 100%
• Mannitol 100%
• Pharmacokinetics 100%
• P-Glycoprotein 100%
• In Vitro Screening 100%

Immunology and Microbiology

• Drug Penetration 100%
• Epithelial Cell Line 100%
• Absorption 100%
• Morphology 50%
• Cell Culture 50%
• P-Glycoprotein 50%
• Preclinical Study 50%
• Electric Resistance 50%
• Pharmacokinetics 50%