Evaluation of linezolid for the treatment of Clostridium difficile infection caused by epidemic strains using an in vitro human gut model

Simon D. Baines, Alan R. Noel, Grace S. Huscroft, Sharie L. Todhunter, Rachael O'Connor, Joanne K. Hobbs, Jane Freeman, Andy M. Lovering, M. H. Wilcox

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Therapeutic options in Clostridium difficile infection (CDI) are limited. We examined linezolid activity in vitro and potential therapeutic efficacy using a gut model of CDI.
Original languageEnglish
Pages (from-to)1537-46
Number of pages10
JournalJournal of Antimicrobial Chemotherapy
Volume66
Issue number7
DOIs
Publication statusPublished - 2011

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