Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide

M. Reimann; K. Vafeiadou; W. L. Hall; J. Dierkes; M. Nilsson; K. Dahlman-Wright; M. Ferrari; U. Huebner; J. Hallund; S. Bugel; F. Branca; C. M. Williams; C. Koebnick

doi:10.1080/13697130600733758

Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide

M. Reimann, K. Vafeiadou, W. L. Hall, J. Dierkes, M. Nilsson, K. Dahlman-Wright, M. Ferrari, U. Huebner, J. Hallund, S. Bugel, F. Branca, C. M. Williams, C. Koebnick

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Homocysteine and asymmetric dimethylarginine (ADMA) affect nitric oxide (NO) concentration, thereby contributing to cardiovascular disease (CVD). Both amino acids can be reduced in vivo by estrogen. Variation in the estrogen receptor (ER) may influence homocysteine and ADMA, yet no information is available on associations with single nucleotide polymorphisms in the estrogen receptor genes ERalpha (PvuII and XbaI) and ERbeta (1730G-->A and cx + 56 G-->A).

Original language	English
Pages (from-to)	215-23
Number of pages	9
Journal	Climacteric : the Journal of the International Menopause Society
Volume	9
Issue number	3
DOIs	https://doi.org/10.1080/13697130600733758
Publication status	Published - Jun 2006

Keywords

Aged
Arginine
Body Mass Index
Cardiovascular Diseases
Cross-Sectional Studies
Estrogen Receptor alpha
Estrogen Receptor beta
Female
Folic Acid
Genetic Variation
Genotype
Homocysteine
Humans
Linkage Disequilibrium
Middle Aged
Nitric Oxide
Nitric Oxide Synthase
Polymorphism, Single Nucleotide
Postmenopause
Risk Factors
Vitamin B 12

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10.1080/13697130600733758

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Reimann, M., Vafeiadou, K., Hall, W. L., Dierkes, J., Nilsson, M., Dahlman-Wright, K., Ferrari, M., Huebner, U., Hallund, J., Bugel, S., Branca, F., Williams, C. M., & Koebnick, C. (2006). Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide. Climacteric : the Journal of the International Menopause Society, 9(3), 215-23. https://doi.org/10.1080/13697130600733758

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title = "Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide",

abstract = "Homocysteine and asymmetric dimethylarginine (ADMA) affect nitric oxide (NO) concentration, thereby contributing to cardiovascular disease (CVD). Both amino acids can be reduced in vivo by estrogen. Variation in the estrogen receptor (ER) may influence homocysteine and ADMA, yet no information is available on associations with single nucleotide polymorphisms in the estrogen receptor genes ERalpha (PvuII and XbaI) and ERbeta (1730G-->A and cx + 56 G-->A).",

keywords = "Aged, Arginine, Body Mass Index, Cardiovascular Diseases, Cross-Sectional Studies, Estrogen Receptor alpha, Estrogen Receptor beta, Female, Folic Acid, Genetic Variation, Genotype, Homocysteine, Humans, Linkage Disequilibrium, Middle Aged, Nitric Oxide, Nitric Oxide Synthase, Polymorphism, Single Nucleotide, Postmenopause, Risk Factors, Vitamin B 12",

author = "M. Reimann and K. Vafeiadou and Hall, {W. L.} and J. Dierkes and M. Nilsson and K. Dahlman-Wright and M. Ferrari and U. Huebner and J. Hallund and S. Bugel and F. Branca and Williams, {C. M.} and C. Koebnick",

year = "2006",

month = jun,

doi = "10.1080/13697130600733758",

language = "English",

volume = "9",

pages = "215--23",

journal = "Climacteric : the Journal of the International Menopause Society",

issn = "1369-7137",

publisher = "Informa Healthcare",

number = "3",

}

Reimann, M, Vafeiadou, K, Hall, WL, Dierkes, J, Nilsson, M, Dahlman-Wright, K, Ferrari, M, Huebner, U, Hallund, J, Bugel, S, Branca, F, Williams, CM & Koebnick, C 2006, 'Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide', Climacteric : the Journal of the International Menopause Society, vol. 9, no. 3, pp. 215-23. https://doi.org/10.1080/13697130600733758

TY - JOUR

T1 - Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide

AU - Reimann, M.

AU - Vafeiadou, K.

AU - Hall, W. L.

AU - Dierkes, J.

AU - Nilsson, M.

AU - Dahlman-Wright, K.

AU - Ferrari, M.

AU - Huebner, U.

AU - Hallund, J.

AU - Bugel, S.

AU - Branca, F.

AU - Williams, C. M.

AU - Koebnick, C.

PY - 2006/6

Y1 - 2006/6

N2 - Homocysteine and asymmetric dimethylarginine (ADMA) affect nitric oxide (NO) concentration, thereby contributing to cardiovascular disease (CVD). Both amino acids can be reduced in vivo by estrogen. Variation in the estrogen receptor (ER) may influence homocysteine and ADMA, yet no information is available on associations with single nucleotide polymorphisms in the estrogen receptor genes ERalpha (PvuII and XbaI) and ERbeta (1730G-->A and cx + 56 G-->A).

AB - Homocysteine and asymmetric dimethylarginine (ADMA) affect nitric oxide (NO) concentration, thereby contributing to cardiovascular disease (CVD). Both amino acids can be reduced in vivo by estrogen. Variation in the estrogen receptor (ER) may influence homocysteine and ADMA, yet no information is available on associations with single nucleotide polymorphisms in the estrogen receptor genes ERalpha (PvuII and XbaI) and ERbeta (1730G-->A and cx + 56 G-->A).

KW - Aged

KW - Arginine

KW - Body Mass Index

KW - Cardiovascular Diseases

KW - Cross-Sectional Studies

KW - Estrogen Receptor alpha

KW - Estrogen Receptor beta

KW - Female

KW - Folic Acid

KW - Genetic Variation

KW - Genotype

KW - Homocysteine

KW - Humans

KW - Linkage Disequilibrium

KW - Middle Aged

KW - Nitric Oxide

KW - Nitric Oxide Synthase

KW - Polymorphism, Single Nucleotide

KW - Postmenopause

KW - Risk Factors

KW - Vitamin B 12

U2 - 10.1080/13697130600733758

DO - 10.1080/13697130600733758

M3 - Article

C2 - 16766435

SN - 1369-7137

VL - 9

SP - 215

EP - 223

JO - Climacteric : the Journal of the International Menopause Society

JF - Climacteric : the Journal of the International Menopause Society

IS - 3

ER -

Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide

Abstract

Keywords

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