Evolutionary targeted discovery of influenza A virus replication inhibitors

Keyphrases

• Influenza Virus 100%
• Virus Replication 100%
• Evolutionary 100%
• Replication Inhibitor 100%
• Influenza A 100%
• Binding Hotspots 100%
• Protein Conservation 66%
• Antiviral Drugs 66%
• Non-structural Protein 66%
• Polymerase Basic Protein 2 66%
• Nuclear Export Signal 66%
• Conservation Analysis 66%
• Binding Affinity 66%
• M2 Protein 33%
• Amino Acid Residues 33%
• Influenza A H1N1 33%
• I-TASSER 33%
• Computational Solvent Mapping 33%
• Viral Infection 33%
• AutoDock Vina 33%
• Amino Acid Conservation 33%
• Highly Conserved Regions 33%
• Compound Library 33%
• Drug Target 33%
• Neuraminidase 33%
• Binding Site 33%
• Mechanism of Action 33%
• Antiviral Drug Resistance 33%
• Ligand Binding 33%
• Treatment Options 33%
• In Vitro Experiment 33%
• Plaque Reduction Assay 33%
• Virtual Screening 33%
• Scoring Method 33%
• Hit Compound 33%
• Autodock 4.2 33%
• Conserved Amino Acids 33%
• Conserved Residues 33%
• Conserved Regions 33%
• Missing Parts 33%
• Experimental Structure 33%

Medicine and Dentistry

• Influenza A 100%
• Virus Replication 100%
• Influenza A Virus 100%
• Evolution 100%
• Antivirus Agent 66%
• AutoDock 66%
• Binding Affinity 66%
• Polymerase 66%
• Nuclear Export 66%
• Nonstructural Protein 1 66%
• Basic Protein 66%
• Amino Acid 66%
• Pandemic 33%
• Target Protein 33%
• In Vitro 33%
• Infection 33%
• Protein M2 33%
• Binding Site 33%
• Virus Infection 33%
• Sialidase 33%
• Drug Delivery System 33%
• Ligand Binding 33%
• Influenza A (H1N1) 33%
• Virtual Screening 33%
• Antiviral Resistance 33%

Biochemistry, Genetics and Molecular Biology

• Evolution 100%
• Amino Acids 100%
• Structural Protein 100%
• Influenza A Virus 100%
• AutoDock 100%
• Polymerase 100%
• Nuclear Export 100%
• Binding Affinity 100%
• Virus Replication 100%
• Synapsin I 100%
• Ligand Binding 50%
• Influenza A Virus (H1N1) 50%
• Antiviral Resistance 50%
• Sialidase 50%
• Neuraminidase 50%
• Binding Site 50%
• Drug Targeting 50%