TY - JOUR
T1 - Exploring the association of dairy product intake with the fatty acids C15:0 and C17:0 measured from dried blood spots in a multi-population cohort
T2 - findings from the Food4Me study
AU - Albani, Viviana
AU - Celis-Morales, Carlos
AU - Marsaux, Cyril F. M.
AU - Forster, Hannah
AU - O'Donovan, Clare B.
AU - Woolhead, Clara
AU - Macready, Anna L.
AU - Fallaize, Rosalind
AU - Navas-Carretero, Santiago
AU - San-Cristobal, Rodrigo
AU - Kolossa, Silvia
AU - Mavrogianni, Christina
AU - Lambrinou, Christina P.
AU - Moschonis, George
AU - Godlewska, Magdalena
AU - Surwiłło, Agnieszka
AU - Gundersen, Thomas E.
AU - Kaland, Siv E.
AU - Manios, Yannis
AU - Traczyk, Iwona
AU - Drevon, Christian A.
AU - Gibney, Eileen R.
AU - Walsh, Marianne C.
AU - Martinez, J. Alfredo
AU - Saris, Wim H. M.
AU - Daniel, Hannelore
AU - Lovegrove, Julie A.
AU - Gibney, Michael J.
AU - Adamson, Ashley J.
AU - Mathers, John C.
AU - Brennan, Lorraine
AU - Food4Me Study
N1 - This article is protected by copyright. All rights reserved.
PY - 2016/4
Y1 - 2016/4
N2 - SCOPE: The use of biomarkers in the objective assessment of dietary intake is a high priority in nutrition research. The aim of this study was to examine pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0) as biomarkers of dairy foods intake.METHODS AND RESULTS: The data used in the present study were obtained as part of the Food4me Study. Estimates of C15:0 and C17:0 from dried blood spots and intakes of dairy from an FFQ were obtained from participants (n = 1,180) across 7 countries. Regression analyses were used to explore associations of biomarkers with dairy intake levels and receiver operating characteristic (ROC) analyses were used to evaluate the fatty acids. Significant positive associations were found between C15:0 and total intakes of high-fat dairy products. C15:0 showed good ability to distinguish between low and high consumers of high-fat dairy products.CONCLUSION: C15:0 can be used as a biomarker of high-fat dairy intake and of specific high-fat dairy products. Both C15:0 and C17:0 performed poorly for total dairy intake highlighting the need for caution when using these in epidemiological studies. This article is protected by copyright. All rights reserved.
AB - SCOPE: The use of biomarkers in the objective assessment of dietary intake is a high priority in nutrition research. The aim of this study was to examine pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0) as biomarkers of dairy foods intake.METHODS AND RESULTS: The data used in the present study were obtained as part of the Food4me Study. Estimates of C15:0 and C17:0 from dried blood spots and intakes of dairy from an FFQ were obtained from participants (n = 1,180) across 7 countries. Regression analyses were used to explore associations of biomarkers with dairy intake levels and receiver operating characteristic (ROC) analyses were used to evaluate the fatty acids. Significant positive associations were found between C15:0 and total intakes of high-fat dairy products. C15:0 showed good ability to distinguish between low and high consumers of high-fat dairy products.CONCLUSION: C15:0 can be used as a biomarker of high-fat dairy intake and of specific high-fat dairy products. Both C15:0 and C17:0 performed poorly for total dairy intake highlighting the need for caution when using these in epidemiological studies. This article is protected by copyright. All rights reserved.
U2 - 10.1002/mnfr.201500483
DO - 10.1002/mnfr.201500483
M3 - Article
C2 - 26678873
SN - 1613-4125
VL - 60
SP - 834
EP - 845
JO - Molecular Nutrition and Food Research
JF - Molecular Nutrition and Food Research
IS - 4
ER -