Grid-based storage architecture for accelerating bioinformatics computing

Frank Wang, Na Helian, Sining Wu, Yuhui Deng, Vineet Khare, chris Thompson

Research output: Contribution to journalArticlepeer-review

Abstract

This paper examines and investigates the relationship between bioinformatics data processing and its underlying computing architecture within the context of the International Nucleotide Sequence Database Collaboration (INSDC). INSDC exchanges sequence data on a daily basis across its three member organizations in USA, UK and Japan. We studied how this sequence database in MySQL can best take advantage of the increased transfer bandwidth of a grid-based storage architecture. Within the context of the UK Government Project “Grid-oriented Storage (GOS)” and the EC Project “EuroAsiaGrid,” GOS has been developed in our lab, which melds parallel streaming technique to meet the needs of WAN/Grid-based virtual organizations. A real-world test shows that the INSDC sequence database backuping operation, mysqldump, over the pipelined GOS architecture beats those over the classic …
Original languageEnglish
Pages (from-to)311-324
JournalThe Journal of VLSI Signal Processing Systems for Signal, Image, and Video Technology
DOIs
Publication statusPublished - Sept 2007

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