Health Benefits of Montmorency Tart Cherry Juice Supplementation in Adults with Mild to Moderate Ulcerative Colitis: A Protocol fo a Placebo Randomised Controlled Trial

Jonathan Sinclair, Stephanie Dillon, Robert Allan, Johanne Brooks-Warburton , Terun Desai, Charlotte Lawson, Lindsay Bottoms

Research output: Contribution to journalArticlepeer-review

23 Downloads (Pure)

Abstract

Ulcerative colitis, characterized by its relapsing and remissive nature, negatively affects perception, body image, and overall quality of life. The associated financial burden underscores the need for alternative treatment approaches with fewer side effects, alongside pharmaceutical interventions. Montmorency tart cherries, rich in anthocyanins, have emerged as a potential natural anti-inflammatory agent for ulcerative colitis. This manuscript outlines the study protocol for a randomized placebo-controlled trial investigating the effects of Montmorency tart cherry in individuals with ulcerative colitis. The trial aims to recruit 40 participants with mild to moderate disease activity randomly assign them to either a Montmorency tart cherry or placebo group. The intervention will span 6 weeks, with baseline and 6-week assessments. The primary outcome measure is the Inflammatory Bowel Disease Quality of Life Questionnaire. Secondary outcomes include other health-related questionnaires and biological indices. Statistical analysis will adhere to an intention-to-treat approach using linear mixed effect models. Ethical approval has been obtained from the University of Hertfordshire (cLMS/SF/UH/05240), and the trial has been registered as a clinical trial (NCT05486507). The trial findings will be disseminated through a peer-reviewed publication in a scientific journal.
Original languageEnglish
Article number76
Pages (from-to)1-10
Number of pages10
JournalMethods and Protocols
Volume6
Issue number5
Early online date23 Aug 2023
DOIs
Publication statusPublished - 27 Aug 2023

Fingerprint

Dive into the research topics of 'Health Benefits of Montmorency Tart Cherry Juice Supplementation in Adults with Mild to Moderate Ulcerative Colitis: A Protocol fo a Placebo Randomised Controlled Trial'. Together they form a unique fingerprint.

Cite this