Hierarchical Self-Organising Decision Support System for the Management of Septic Shock Patients

O.K. King, M. Mahfouf, Mouloud Denai, J.J. Ross, M. Abbod

    Research output: Contribution to conferencePaper

    1 Citation (Scopus)


    An on-line intelligent advisory system (IAS) for the management of septic patients emerging from cardiopulmonary bypass (CPB) has been developed and evaluated on a comprehensive physiological model which incorporates sepsis-induced capillary leak and the hemodynamic response to ICU-like therapeutic interventions. The IAS is composed of the expert’s decision-making model which performs diagnosis and designates the appropriate therapeutic actions based on the patient’s hemodynamic status and a multi-inputs multi-outputs self-organising fuzzy logic controller (SOFLC) for adjusting the infusion rates of the selected drugs to maintain the hemodynamics variables at the specified target values. Simulated patient scenarios reproducing post-CPB hemodynamic abnormalities were developed with the expert anesthetist to test the IAS ability to advice for the appropriate therapeutic interventions whilst controlling individual drugs infusion rates to maintain the hemodynamic parameters at the prescribed targets values
    Original languageEnglish
    Publication statusPublished - 2011
    Event18th IFAC World Congress - Milan, Italy
    Duration: 28 Aug 20112 Sept 2011


    Conference18th IFAC World Congress


    Dive into the research topics of 'Hierarchical Self-Organising Decision Support System for the Management of Septic Shock Patients'. Together they form a unique fingerprint.

    Cite this