How hosts control worms

M.J. Stear, K. Bairden, J.L. Duncan, P.H. Holmes, Quintin McKellar, M. Park, S. Strain, M. Murray, S.C. Bishop, G. Gettinby

Research output: Contribution to journalComment/debatepeer-review

86 Citations (Scopus)
38 Downloads (Pure)


Nematodes are a major cause of disease and death in humans, domestic animals and wildlife. Understanding why some individuals suffer severely whereas others exposed to the same infection remain healthy may assist in the development of rational and sustainable strategies to control infection. Here, using a quantitative genetic analysis of the parasitic nematode population that had accumulated naturally in lambs, we find no apparent influence of host genetics on nematode numbers but an extremely strong influence on average worm length and fecundity. Our results indicate that in growing lambs the main manifestation of genetic resistance is the control of worm fecundity
Original languageEnglish
Pages (from-to)27
Number of pages1
Issue number6646
Publication statusPublished - 4 Sept 1997




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