How to become attached to a nematode: new developments in Pasteuria endospore adhesion to juvenile cuticle

Keith Davies, Arohi Srivastava, Victor Phani

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Pasteuria penetrans is a Gram-positive endospore forming bacteria that has potential to be developed into a biological control agent of plant-parasitic nematodes. If this bacterium is to be deployed to control nematodes in the field an understanding of the biochemistry and the underpinning molecular biology by which it adheres to one nematode but not another is key. A Velcro-like attachment process has been hypothesised and currently we have identified and started to characterise a number of collagen-like sequences from Pasteuria that are glycosylated and present on the endospore surface. We believe these fibrous structures that produce a hair-like nap on the surface of the endospore are important in the initial endospore attachment process to the nematode cuticle. Regarding the nematode cuticle to which the endospores bind we have identified two genes, that code for a FAR-protein and a mucin-like protein, that when knocked down affect endospore attachment.
Original languageEnglish
Title of host publicationProceedings of the 70th International Symposium of Crop Protection
Place of PublicationGhent, Belgium
Publication statusPublished - 22 May 2018
Event70th International Symposium of Crop protection - Ghent University, Ghent, Belgium
Duration: 22 May 201822 May 2018


Conference70th International Symposium of Crop protection
Abbreviated titleISCP


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