Impaired executive functioning after left anterior insular stroke: a case report

Ioanna Markostamou, Jobst Rudolf, Iakovos Tsiptsios, Mary H. Kosmidis

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Given the insular’s anatomic complexity and functional interconnectivity, acute lesions may result in varied clinical presentations, including autonomic, somatosensory, perceptual, motor, affective, and cognitive deficits. Although functional neuroimaging studies have demonstrated its role in executive functions, no clinical manifestations have been reported to date. We present the case of a woman with an acute left anterior insular infarction leading to executive (i.e., word and design fluency, mental flexibility, sustained attention, inhibitory control), but not language, visuoperceptual, or memory impairment. This case confirms the left anterior insula’s involvement in executive functioning and suggests that an infarction may result in executive impairment.

Original languageEnglish
Pages (from-to)148-153
Number of pages6
Issue number2
Early online date6 Feb 2014
Publication statusPublished - 4 Mar 2015


  • executive functioning
  • insula
  • lesion
  • stroke


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