In-Vivo Hyperspectral Human Brain Image Database for Brain Cancer Detection

Himar Fabelo, Samuel Ortega, Adam Szolna, Diederik Bulters, Juan F. Pineiro, Silvester Kabwama, Aruma J-O'Shanahan, Harry Bulstrode, Sara Bisshopp, B. Ravi Kiran, Daniele Ravi, Raquel Lazcano, Daniel Madronal, Coralia Sosa, Carlos Espino, Mariano Marquez, Maria De La Luz Plaza, Rafael Camacho, David Carrera, Maria HernandezGustavo M. Callico, Jesus Morera Molina, Bogdan Stanciulescu, Guang Zhong Yang, Ruben Salvador Perea, Eduardo Juarez, Cesar Sanz, Roberto Sarmiento

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


The use of hyperspectral imaging for medical applications is becoming more common in recent years. One of the main obstacles that researchers find when developing hyperspectral algorithms for medical applications is the lack of specific, publicly available, and hyperspectral medical data. The work described in this paper was developed within the framework of the European project HELICoiD (HypErspectraL Imaging Cancer Detection), which had as a main goal the application of hyperspectral imaging to the delineation of brain tumors in real-time during neurosurgical operations. In this paper, the methodology followed to generate the first hyperspectral database of in-vivo human brain tissues is presented. Data was acquired employing a customized hyperspectral acquisition system capable of capturing information in the Visual and Near InfraRed (VNIR) range from 400 to 1000 nm. Repeatability was assessed for the cases where two images of the same scene were captured consecutively. The analysis reveals that the system works more efficiently in the spectral range between 450 and 900 nm. A total of 36 hyperspectral images from 22 different patients were obtained. From these data, more than 300 000 spectral signatures were labeled employing a semi-automatic methodology based on the spectral angle mapper algorithm. Four different classes were defined: normal tissue, tumor tissue, blood vessel, and background elements. All the hyperspectral data has been made available in a public repository.

Original languageEnglish
Article number6287639
Pages (from-to)39098-39116
Number of pages19
JournalIEEE Access
Publication statusPublished - 2019


  • biomedical imaging
  • cancer detection
  • Hyperspectral imaging
  • image databases
  • medical diagnostic imaging


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