Induction Based Detection of Magnetic Particles Via Phase Locked Loop

Sara Chaychian, Wamadeva Balachandran , Yichuang Sun

Research output: Chapter in Book/Report/Conference proceedingConference contribution


This study describes the process of designing an induction based sensor for magnetic particle detection. The sensor performance is verified by the means of practical experiments. An oscillator circuit integrated with voltage comparators and phase locked loop was used to investigate the effect of magnetic particle mass on the resonance frequency of the sensor. The core of the sensing system is the circular air-core inductor which generates magnetic field and polarizes the magnetic beads in its vicinity. Differential sensing scheme is implemented to minimize environmental interfaces and suppress any low-frequency fluctuations. The sensor is resonating at 2.7MHz of frequency. The frequency shift of 142 Hz was achieved in the presence of 10μL of magnetic particles with 10nm bead size. This sensing setup can be used for molecular DNA hybridization detection and point of care diagnostics.
Original languageEnglish
Title of host publication2020 IEEE 63rd International Midwest Symposium on Circuits and Systems, MWSCAS 2020 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Number of pages5
ISBN (Electronic)9781538629161
Publication statusPublished - 9 Aug 2020

Publication series

NameMidwest Symposium on Circuits and Systems
ISSN (Print)1548-3746


  • DNA hybridization Detection
  • Induction based Sensor
  • Magnetic Beads
  • Magnetic Biosensor
  • Magnetic Particle Detection
  • Magnetic labels


Dive into the research topics of 'Induction Based Detection of Magnetic Particles Via Phase Locked Loop'. Together they form a unique fingerprint.

Cite this