Integrated 18F-FDG PET/CT and perfusion CT of primary colorectal cancer: effect of inter- and intraobserver agreement on metabolic-vascular parameters

Vicky  Goh; Manu Shastry; Alec Engledow; Robert Kozarski; Jacqui Peck; Raymondo Endozo; Manuel Rodriguez-Justo; Stuart A Taylor; Steve Halligan; Ashley M Groves

doi:10.2214/AJR.11.7823

Integrated 18F-FDG PET/CT and perfusion CT of primary colorectal cancer: effect of inter- and intraobserver agreement on metabolic-vascular parameters

Vicky Goh, Manu Shastry, Alec Engledow, Robert Kozarski, Jacqui Peck, Raymondo Endozo, Manuel Rodriguez-Justo, Stuart A Taylor, Steve Halligan, Ashley M Groves

School of Life and Medical Sciences

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

The purpose of this article is to assess the effect of observers on combined metabolic-vascular parameters in colorectal cancer. Twenty-five prospective patients (12 men and 13 women; mean age, 66.9 years) with proven primary colorectal adenocarcinoma underwent integrated ¹⁸F-FDG PET/perfusion CT to assess tumor metabolism (mean and maximum standardized uptake value [SUV_mean and SUV_max, respectively]) and vascularization (blood flow [BF], blood volume [BV], permeability surface-area product, and standardized perfusion value). Intra- and interobserver agreement for PET, perfusion CT, and combined metabolic-flow parameters were determined by Bland-Altman statistics and intraclass correlation coefficients (ICCs).

Original language	English
Pages (from-to)	1003-1009
Journal	American Journal of Roentgenology
Volume	199
Issue number	5
DOIs	https://doi.org/10.2214/AJR.11.7823
Publication status	Published - Nov 2012

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Goh, V., Shastry, M., Engledow, A., Kozarski, R., Peck, J., Endozo, R., Rodriguez-Justo, M., Taylor, S. A., Halligan, S., & Groves, A. M. (2012). Integrated 18F-FDG PET/CT and perfusion CT of primary colorectal cancer: effect of inter- and intraobserver agreement on metabolic-vascular parameters. American Journal of Roentgenology, 199(5), 1003-1009. https://doi.org/10.2214/AJR.11.7823

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title = "Integrated 18F-FDG PET/CT and perfusion CT of primary colorectal cancer: effect of inter- and intraobserver agreement on metabolic-vascular parameters",

abstract = "The purpose of this article is to assess the effect of observers on combined metabolic-vascular parameters in colorectal cancer. Twenty-five prospective patients (12 men and 13 women; mean age, 66.9 years) with proven primary colorectal adenocarcinoma underwent integrated 18F-FDG PET/perfusion CT to assess tumor metabolism (mean and maximum standardized uptake value [SUVmean and SUVmax, respectively]) and vascularization (blood flow [BF], blood volume [BV], permeability surface-area product, and standardized perfusion value). Intra- and interobserver agreement for PET, perfusion CT, and combined metabolic-flow parameters were determined by Bland-Altman statistics and intraclass correlation coefficients (ICCs).",

author = "Vicky Goh and Manu Shastry and Alec Engledow and Robert Kozarski and Jacqui Peck and Raymondo Endozo and Manuel Rodriguez-Justo and Taylor, \{Stuart A\} and Steve Halligan and Groves, \{Ashley M\}",

year = "2012",

month = nov,

doi = "10.2214/AJR.11.7823",

language = "English",

volume = "199",

pages = "1003--1009",

journal = "American Journal of Roentgenology",

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publisher = "American Roentgen Ray Society",

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Goh, V, Shastry, M, Engledow, A, Kozarski, R, Peck, J, Endozo, R, Rodriguez-Justo, M, Taylor, SA, Halligan, S & Groves, AM 2012, 'Integrated 18F-FDG PET/CT and perfusion CT of primary colorectal cancer: effect of inter- and intraobserver agreement on metabolic-vascular parameters', American Journal of Roentgenology, vol. 199, no. 5, pp. 1003-1009. https://doi.org/10.2214/AJR.11.7823

TY - JOUR

T1 - Integrated 18F-FDG PET/CT and perfusion CT of primary colorectal cancer

T2 - effect of inter- and intraobserver agreement on metabolic-vascular parameters

AU - Goh, Vicky

AU - Shastry, Manu

AU - Engledow, Alec

AU - Kozarski, Robert

AU - Peck, Jacqui

AU - Endozo, Raymondo

AU - Rodriguez-Justo, Manuel

AU - Taylor, Stuart A

AU - Halligan, Steve

AU - Groves, Ashley M

PY - 2012/11

Y1 - 2012/11

N2 - The purpose of this article is to assess the effect of observers on combined metabolic-vascular parameters in colorectal cancer. Twenty-five prospective patients (12 men and 13 women; mean age, 66.9 years) with proven primary colorectal adenocarcinoma underwent integrated 18F-FDG PET/perfusion CT to assess tumor metabolism (mean and maximum standardized uptake value [SUVmean and SUVmax, respectively]) and vascularization (blood flow [BF], blood volume [BV], permeability surface-area product, and standardized perfusion value). Intra- and interobserver agreement for PET, perfusion CT, and combined metabolic-flow parameters were determined by Bland-Altman statistics and intraclass correlation coefficients (ICCs).

AB - The purpose of this article is to assess the effect of observers on combined metabolic-vascular parameters in colorectal cancer. Twenty-five prospective patients (12 men and 13 women; mean age, 66.9 years) with proven primary colorectal adenocarcinoma underwent integrated 18F-FDG PET/perfusion CT to assess tumor metabolism (mean and maximum standardized uptake value [SUVmean and SUVmax, respectively]) and vascularization (blood flow [BF], blood volume [BV], permeability surface-area product, and standardized perfusion value). Intra- and interobserver agreement for PET, perfusion CT, and combined metabolic-flow parameters were determined by Bland-Altman statistics and intraclass correlation coefficients (ICCs).

U2 - 10.2214/AJR.11.7823

DO - 10.2214/AJR.11.7823

M3 - Article

SN - 1546-3141

VL - 199

SP - 1003

EP - 1009

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

IS - 5

ER -

Integrated 18F-FDG PET/CT and perfusion CT of primary colorectal cancer: effect of inter- and intraobserver agreement on metabolic-vascular parameters

Abstract

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