Intercellular communication in smooth muscle

J.D. Huizinga; L.W.C. Liu; M.G. Blennerhassett; L. Thuneberg; A. Molleman

doi:10.1007/BF01919140

Intercellular communication in smooth muscle

J.D. Huizinga, L.W.C. Liu, M.G. Blennerhassett, L. Thuneberg, A. Molleman

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Abstract

The functioning of a group of cells as a tissue depends on intercellular communication; an example is the spread of action potentials through intestinal tissue resulting in synchronized contraction. Recent evidence for cell heterogeneity within smooth muscle tissues has renewed research into cell coupling.Electrical coupling is essential for propagation of action potentials in gastrointestinal smooth muscle.Metabolic coupling may be involved in generation of pacemaker activity. This review deals with the role of cell coupling in tissue function and some of the issues discussed are the relationship between electrical synchronization and gap junctions, metabolic coupling, and the role of interstitial cells of Cajal in coupling.

Original language	English
Pages (from-to)	932-941
Journal	Cellular and Molecular Life Sciences
Volume	48
Issue number	10
DOIs	https://doi.org/10.1007/BF01919140
Publication status	Published - 1992

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10.1007/BF01919140

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title = "Intercellular communication in smooth muscle",

abstract = "The functioning of a group of cells as a tissue depends on intercellular communication; an example is the spread of action potentials through intestinal tissue resulting in synchronized contraction. Recent evidence for cell heterogeneity within smooth muscle tissues has renewed research into cell coupling.Electrical coupling is essential for propagation of action potentials in gastrointestinal smooth muscle.Metabolic coupling may be involved in generation of pacemaker activity. This review deals with the role of cell coupling in tissue function and some of the issues discussed are the relationship between electrical synchronization and gap junctions, metabolic coupling, and the role of interstitial cells of Cajal in coupling.",

author = "J.D. Huizinga and L.W.C. Liu and M.G. Blennerhassett and L. Thuneberg and A. Molleman",

note = "' The original publication is available at www.springerlink.com ' Copyright Springer. DOI: 10.1007/BF01919140 [Full text of this article is not available in the UHRA]",

year = "1992",

doi = "10.1007/BF01919140",

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volume = "48",

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journal = "Cellular and Molecular Life Sciences",

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TY - JOUR

T1 - Intercellular communication in smooth muscle

AU - Huizinga, J.D.

AU - Liu, L.W.C.

AU - Blennerhassett, M.G.

AU - Thuneberg, L.

AU - Molleman, A.

N1 - ' The original publication is available at www.springerlink.com ' Copyright Springer. DOI: 10.1007/BF01919140 [Full text of this article is not available in the UHRA]

PY - 1992

Y1 - 1992

N2 - The functioning of a group of cells as a tissue depends on intercellular communication; an example is the spread of action potentials through intestinal tissue resulting in synchronized contraction. Recent evidence for cell heterogeneity within smooth muscle tissues has renewed research into cell coupling.Electrical coupling is essential for propagation of action potentials in gastrointestinal smooth muscle.Metabolic coupling may be involved in generation of pacemaker activity. This review deals with the role of cell coupling in tissue function and some of the issues discussed are the relationship between electrical synchronization and gap junctions, metabolic coupling, and the role of interstitial cells of Cajal in coupling.

AB - The functioning of a group of cells as a tissue depends on intercellular communication; an example is the spread of action potentials through intestinal tissue resulting in synchronized contraction. Recent evidence for cell heterogeneity within smooth muscle tissues has renewed research into cell coupling.Electrical coupling is essential for propagation of action potentials in gastrointestinal smooth muscle.Metabolic coupling may be involved in generation of pacemaker activity. This review deals with the role of cell coupling in tissue function and some of the issues discussed are the relationship between electrical synchronization and gap junctions, metabolic coupling, and the role of interstitial cells of Cajal in coupling.

U2 - 10.1007/BF01919140

DO - 10.1007/BF01919140

M3 - Article

SN - 1420-682X

VL - 48

SP - 932

EP - 941

JO - Cellular and Molecular Life Sciences

JF - Cellular and Molecular Life Sciences

IS - 10

ER -

Intercellular communication in smooth muscle

Abstract

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