Investigation of skin permeation using ATR-FTIR spectroscopic imaging and multivariate target factor analysis

K. T. Mader; J. Tetteh; W. J. McAuley; M. E. Lane; J. Hadgraft; J. M. Andanson; S. G. Kazarian

doi:10.1111/j.2042-7158.2010.01178.x

Investigation of skin permeation using ATR-FTIR spectroscopic imaging and multivariate target factor analysis

K. T. Mader, J. Tetteh, W. J. McAuley, M. E. Lane, J. Hadgraft, J. M. Andanson, S. G. Kazarian

Research output: Contribution to journal › Special issue › peer-review

3 Citations (Scopus)

Abstract

ATR-FTIR spectroscopic imaging permeation experiments of a model formulation across stratum corneum (SC) were conducted to acquire further understanding
of the mechanism of drug permeation. Quantitative iterative target transformation factor analysis (QITTFA) was used for the analysis of the complex and
highly overlapping spectroscopic data generated.

Original language	English
Pages (from-to)	1279-1280
Number of pages	2
Journal	Journal of Pharmacy and Pharmacology
Volume	62
Issue number	10
DOIs	https://doi.org/10.1111/j.2042-7158.2010.01178.x
Publication status	Published - Oct 2010

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title = "Investigation of skin permeation using ATR-FTIR spectroscopic imaging and multivariate target factor analysis",

abstract = "ATR-FTIR spectroscopic imaging permeation experiments of a model formulation across stratum corneum (SC) were conducted to acquire further understanding of the mechanism of drug permeation. Quantitative iterative target transformation factor analysis (QITTFA) was used for the analysis of the complex and highly overlapping spectroscopic data generated.",

author = "Mader, {K. T.} and J. Tetteh and McAuley, {W. J.} and Lane, {M. E.} and J. Hadgraft and Andanson, {J. M.} and Kazarian, {S. G.}",

note = "The definitive version can be found at: http://onlinelibrary.wiley.com/ Copyright Wiley-Blackwell [Full text of this paper is not available in the UHRA]",

year = "2010",

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doi = "10.1111/j.2042-7158.2010.01178.x",

language = "English",

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journal = "Journal of Pharmacy and Pharmacology",

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TY - JOUR

T1 - Investigation of skin permeation using ATR-FTIR spectroscopic imaging and multivariate target factor analysis

AU - Mader, K. T.

AU - Tetteh, J.

AU - McAuley, W. J.

AU - Lane, M. E.

AU - Hadgraft, J.

AU - Andanson, J. M.

AU - Kazarian, S. G.

N1 - The definitive version can be found at: http://onlinelibrary.wiley.com/ Copyright Wiley-Blackwell [Full text of this paper is not available in the UHRA]

PY - 2010/10

Y1 - 2010/10

N2 - ATR-FTIR spectroscopic imaging permeation experiments of a model formulation across stratum corneum (SC) were conducted to acquire further understanding of the mechanism of drug permeation. Quantitative iterative target transformation factor analysis (QITTFA) was used for the analysis of the complex and highly overlapping spectroscopic data generated.

AB - ATR-FTIR spectroscopic imaging permeation experiments of a model formulation across stratum corneum (SC) were conducted to acquire further understanding of the mechanism of drug permeation. Quantitative iterative target transformation factor analysis (QITTFA) was used for the analysis of the complex and highly overlapping spectroscopic data generated.

U2 - 10.1111/j.2042-7158.2010.01178.x

DO - 10.1111/j.2042-7158.2010.01178.x

M3 - Special issue

VL - 62

SP - 1279

EP - 1280

JO - Journal of Pharmacy and Pharmacology

JF - Journal of Pharmacy and Pharmacology

SN - 0022-3573

IS - 10

ER -

Investigation of skin permeation using ATR-FTIR spectroscopic imaging and multivariate target factor analysis

Abstract

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