Location of a gene conferring DDT resistance but no pyrethroid cross-resistance in larvae of Anopheles stephensi

C A Malcolm

doi:10.1007/BF00057673

Location of a gene conferring DDT resistance but no pyrethroid cross-resistance in larvae of Anopheles stephensi

Research output: Contribution to journal › Article › peer-review

Abstract

In larvae of Anopheles stephensi, DDT resistance of 30 to 40-fold, involving no cross-resistance to pyrethroids, showed fully dominant monofactorial inheritance. The gene, termed DDT, is located 36.6 cross-over units from the morphological mutant, black larvae (Bl), on chromosome III. A polygenic system, which confers a 17-fold reduction in susceptibility to knockdown by the pyrethroid, permethrin, also makes a minor contribution to DDT resistance. It was not possible to block DDT resistance with the dehydrochlorinase inhibitor DMC.

Original language	English
Pages (from-to)	51-5
Number of pages	5
Journal	Genetica
Volume	82
Issue number	1
DOIs	https://doi.org/10.1007/BF00057673
Publication status	Published - 1 Jan 1990

Keywords

Animals
Anopheles/genetics
Chlorobenzenes
Chromosome Mapping
Crosses, Genetic
DDT
Genes
Insecticide Resistance/genetics
Insecticides
Larva/genetics
Permethrin
Pyrethrins

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10.1007/BF00057673

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title = "Location of a gene conferring DDT resistance but no pyrethroid cross-resistance in larvae of Anopheles stephensi",

abstract = "In larvae of Anopheles stephensi, DDT resistance of 30 to 40-fold, involving no cross-resistance to pyrethroids, showed fully dominant monofactorial inheritance. The gene, termed DDT, is located 36.6 cross-over units from the morphological mutant, black larvae (Bl), on chromosome III. A polygenic system, which confers a 17-fold reduction in susceptibility to knockdown by the pyrethroid, permethrin, also makes a minor contribution to DDT resistance. It was not possible to block DDT resistance with the dehydrochlorinase inhibitor DMC.",

keywords = "Animals, Anopheles/genetics, Chlorobenzenes, Chromosome Mapping, Crosses, Genetic, DDT, Genes, Insecticide Resistance/genetics, Insecticides, Larva/genetics, Permethrin, Pyrethrins",

author = "Malcolm, {C A}",

year = "1990",

month = jan,

day = "1",

doi = "10.1007/BF00057673",

language = "English",

volume = "82",

pages = "51--5",

journal = "Genetica",

issn = "0016-6707",

publisher = "Springer Nature Link",

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TY - JOUR

T1 - Location of a gene conferring DDT resistance but no pyrethroid cross-resistance in larvae of Anopheles stephensi

AU - Malcolm, C A

PY - 1990/1/1

Y1 - 1990/1/1

N2 - In larvae of Anopheles stephensi, DDT resistance of 30 to 40-fold, involving no cross-resistance to pyrethroids, showed fully dominant monofactorial inheritance. The gene, termed DDT, is located 36.6 cross-over units from the morphological mutant, black larvae (Bl), on chromosome III. A polygenic system, which confers a 17-fold reduction in susceptibility to knockdown by the pyrethroid, permethrin, also makes a minor contribution to DDT resistance. It was not possible to block DDT resistance with the dehydrochlorinase inhibitor DMC.

AB - In larvae of Anopheles stephensi, DDT resistance of 30 to 40-fold, involving no cross-resistance to pyrethroids, showed fully dominant monofactorial inheritance. The gene, termed DDT, is located 36.6 cross-over units from the morphological mutant, black larvae (Bl), on chromosome III. A polygenic system, which confers a 17-fold reduction in susceptibility to knockdown by the pyrethroid, permethrin, also makes a minor contribution to DDT resistance. It was not possible to block DDT resistance with the dehydrochlorinase inhibitor DMC.

KW - Animals

KW - Anopheles/genetics

KW - Chlorobenzenes

KW - Chromosome Mapping

KW - Crosses, Genetic

KW - DDT

KW - Genes

KW - Insecticide Resistance/genetics

KW - Insecticides

KW - Larva/genetics

KW - Permethrin

KW - Pyrethrins

U2 - 10.1007/BF00057673

DO - 10.1007/BF00057673

M3 - Article

C2 - 2286326

SN - 0016-6707

VL - 82

SP - 51

EP - 55

JO - Genetica

JF - Genetica

IS - 1

ER -

Location of a gene conferring DDT resistance but no pyrethroid cross-resistance in larvae of Anopheles stephensi

Abstract

Keywords

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