TY - JOUR
T1 - Mass spectrometric investigation of synthetic glycoside of muramyl dipeptide immobilized on fumed silica surface
AU - Kulik, Tetiana V.
AU - Azizova, Liana R.
AU - Palyanytsya, Borys B.
AU - Zemlyakov, Alexander E.
AU - Tsikalova, Victoria N.
PY - 2010/5/25
Y1 - 2010/5/25
N2 - N-Acetylmuramyl-l-alanyl-d-isoglutamine or muramyl dipeptide is a cleavage product of peptidoglycan by lysozyme. This study explored the use of the temperature-programmed desorption mass spectrometry (TPDMS) in analysis of glycoside of muramyl dipeptide: O-{(4-tert-butylcyclohexyl)-2-acetamido-2,3-dideoxy-β-d-glucopyranoside-3-yl}-d-lactoyl-l-alanyl-d-isoglutamine (MDP) on the surface of fumed silica. Stages of pyrolysis of MDP in condensed state and on the silica surface have been determined. Three stages have been clear identified under pyrolysis of MDP on the silica surface. Kinetic parameters of thermal reactions on the fumed silica surface and in the condensed state have been calculated.
AB - N-Acetylmuramyl-l-alanyl-d-isoglutamine or muramyl dipeptide is a cleavage product of peptidoglycan by lysozyme. This study explored the use of the temperature-programmed desorption mass spectrometry (TPDMS) in analysis of glycoside of muramyl dipeptide: O-{(4-tert-butylcyclohexyl)-2-acetamido-2,3-dideoxy-β-d-glucopyranoside-3-yl}-d-lactoyl-l-alanyl-d-isoglutamine (MDP) on the surface of fumed silica. Stages of pyrolysis of MDP in condensed state and on the silica surface have been determined. Three stages have been clear identified under pyrolysis of MDP on the silica surface. Kinetic parameters of thermal reactions on the fumed silica surface and in the condensed state have been calculated.
KW - Muramyl dipeptide
KW - Pyrolysis
KW - The temperature-programmed desorption mass spectrometry (TPDMS)
UR - http://www.scopus.com/inward/record.url?scp=77953134335&partnerID=8YFLogxK
U2 - 10.1016/j.mseb.2009.12.003
DO - 10.1016/j.mseb.2009.12.003
M3 - Article
AN - SCOPUS:77953134335
SN - 0921-5107
VL - 169
SP - 114
EP - 118
JO - Materials Science and Engineering: B
JF - Materials Science and Engineering: B
IS - 1-3
ER -