Modeling simple and complex active neurons

Erik De Schutter, Volker Steuber

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Citations (Scopus)


Over the last decade the view of how neurons process synaptic input has shifted fundamentally. Previously the common view was that in most neurons largely passive dendrites collect synaptic charge and convey it in a non-linear but still straightforward manner to the soma. 1,2 Recently, it has become accepted that entirely passive dendrites do not exist. 3 The interaction between dendritic voltage-gated conductances and synaptic input has become a major topic of research where quantitative modeling plays an important role. 4,5 But it is not trivial to construct a detailed morphologically correct model with active membrane. Therefore this chapter is built around the question “what is the right level of complexity for a model of an active neuron?".

Original languageEnglish
Title of host publicationComputational Neuroscience
Subtitle of host publicationRealistic Modeling for Experimentalists
PublisherCRC Press
Number of pages25
ISBN (Electronic)9781420039290
ISBN (Print)9780849320682
Publication statusPublished - 1 Jan 2000
Externally publishedYes


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