Abstract
Multidrug-resistant organisms (MDROs) pose a significant global health threat due to their increasing prevalence and limited treatment options. Common MDROs include Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, and methicillin-resistant Staphylococcus aureus (MRSA). These organisms resist treatment through various mechanisms, including enzymatic degradation, efflux pumps, and target site modifications. Microbiology challenges such as delayed detection and limited diagnostic tools complicate their identification. The prevalence of MDROs varies regionally but remains a critical issue worldwide. Evidence-based strategies for managing invasive MDRO infections include antimicrobial stewardship, combination therapies, and novel agents targeting resistant strains. These approaches are vital to improving outcomes and combating resistance.
| Original language | English |
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| Publication status | Published - 10 Sept 2019 |
| Event | Antibiotic Awareness Week Conference - Duration: 18 Nov 2019 → … |
Conference
| Conference | Antibiotic Awareness Week Conference |
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| Period | 18/11/19 → … |
Keywords
- Multidrug-resistant organisms (MDROs)
- antimicrobial resistance
- Antimicrobial Resistance
- Antimicrobial resistance (AMR)
- Antimicrobial Resistance (AMR)
- Antimicrobial stewardship
- Antimicrobial Stewardship (AMS)
- Antimicrobial stewardship competencies
- antimicrobial stewardship (AMS)
- Antimicrobial stewardship programmes
- Antimicrobial stewardship programs
- antibiotic classification
- Antibiotic Guidelines
- Antibiotic prescribing
- world antibiotic awareness
- WAAW
- WHO
- Antibiotic mechanisms of resistance
- EPIDEMIOLOGY
- MDRO
- Diagnostic challenges
- Invasive bacterial infections
- evidence-based medicine
- Evidence-Based Practice
- Antibiotic Stewardship
- Novel antimicrobial agents
- Global Health Challenge
- Global Health