Mycoviruses and their role in fungal pathogenesis

Research output: Contribution to journalReview articlepeer-review

Abstract

Nowadays, the focus of mycovirology research has expanded from plant pathogenic fungi and mycovirus mediated hypovirulence to include insect and human pathogenic fungi together with a range of mycovirus mediated phenotypes, such as hypervirulence, control of endophytic traits, regulation of metabolite production and drug resistance. In fungus-mycovirus-environmental interactions, the environment and both abiotic and biotic factors play crucial roles in whether and how mycovirus mediated phenotypes are manifest. Mycovirus infections result in alterations in the host transcriptome profile, via protein-protein interactions and triggering of antiviral RNA silencing in the fungus. These alterations, in combination with the environmental factors, may result in desirable phenotypic traits for the host, for us and in some cases for both.

Original languageEnglish
Pages (from-to)10-18
Number of pages9
JournalCurrent opinion in microbiology
Volume63
DOIs
Publication statusPublished - Oct 2021
Externally publishedYes

Keywords

  • Fungal Viruses/genetics
  • Fungi/genetics
  • Humans
  • Plant Diseases
  • Plants
  • RNA Interference
  • RNA Viruses/genetics
  • Transcriptome

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