TY - JOUR
T1 - Neuroplastic Responses to Chiropractic Care: Broad Impacts on Pain, Mood, Sleep, and Quality of Life
AU - Haavik, Heidi
AU - Niazi, Imran Khan
AU - Amjad, Imran
AU - Kumari, Nitika
AU - Ghani, Usman
AU - Ashfaque, Moeez
AU - Rashid, Usman
AU - Navid, Muhammad Samran
AU - Kamavuako, Ernest Nlandu
AU - Pujari, Amit N
AU - Holt, Kelly
N1 - © 2024 The Author(s). Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the Creative Commons Attribution License, to view a copy of the license, see: https://creativecommons.org/licenses/by/4.0/
PY - 2024/11/7
Y1 - 2024/11/7
N2 - Objectives: This study aimed to elucidate the mechanisms of chiropractic care using resting electroencephalography (EEG), somatosensory evoked potentials (SEPs), clinical health assessments (Fitbit), and Patient-reported Outcomes Measurement Information System (PROMIS-29). Methods: Seventy-six people with chronic low back pain (mean age ± SD: 45 ± 11 years, 33 female) were randomised into control (n = 38) and chiropractic (n = 38) groups. EEG and SEPs were collected pre and post the first intervention and post 4 weeks of intervention. PROMIS-29 was measured pre and post 4 weeks. Fitbit data were recorded continuously. Results: Spectral analysis of resting EEG showed a significant increase in Theta, Alpha and Beta, and a significant decrease in Delta power in the chiropractic group post intervention. Source localisation revealed a significant increase in Alpha activity within the Default Mode Network (DMN) post intervention and post 4 weeks. A significant decrease in N30 SEP peak amplitude post intervention and post 4 weeks was found in the chiropractic group. Source localisation demonstrated significant changes in Alpha and Beta power within the DMN post-intervention and post 4 weeks. Significant improvements in light sleep stage were observed in the chiropractic group along with enhanced overall quality of life post 4 weeks, including significant reductions in anxiety, depression, fatigue, and pain. Conclusions: These findings indicate that many health benefits of chiropractic care are due to altered brain activity.
AB - Objectives: This study aimed to elucidate the mechanisms of chiropractic care using resting electroencephalography (EEG), somatosensory evoked potentials (SEPs), clinical health assessments (Fitbit), and Patient-reported Outcomes Measurement Information System (PROMIS-29). Methods: Seventy-six people with chronic low back pain (mean age ± SD: 45 ± 11 years, 33 female) were randomised into control (n = 38) and chiropractic (n = 38) groups. EEG and SEPs were collected pre and post the first intervention and post 4 weeks of intervention. PROMIS-29 was measured pre and post 4 weeks. Fitbit data were recorded continuously. Results: Spectral analysis of resting EEG showed a significant increase in Theta, Alpha and Beta, and a significant decrease in Delta power in the chiropractic group post intervention. Source localisation revealed a significant increase in Alpha activity within the Default Mode Network (DMN) post intervention and post 4 weeks. A significant decrease in N30 SEP peak amplitude post intervention and post 4 weeks was found in the chiropractic group. Source localisation demonstrated significant changes in Alpha and Beta power within the DMN post-intervention and post 4 weeks. Significant improvements in light sleep stage were observed in the chiropractic group along with enhanced overall quality of life post 4 weeks, including significant reductions in anxiety, depression, fatigue, and pain. Conclusions: These findings indicate that many health benefits of chiropractic care are due to altered brain activity.
KW - PROMIS-29
KW - chiropractic
KW - default mode network (DMN)
KW - electroencephalogram (EEG)
KW - somatosensory evoked potentials (SEPs)
UR - http://www.scopus.com/inward/record.url?scp=85210166053&partnerID=8YFLogxK
U2 - 10.3390/brainsci14111124
DO - 10.3390/brainsci14111124
M3 - Article
C2 - 39595887
SN - 2076-3425
VL - 14
SP - 1
EP - 31
JO - Brain Sciences
JF - Brain Sciences
IS - 11
M1 - 1124
ER -