New N-acyl amino acid-functionalized biodegradable polyesters for pharmaceutical and biomedical applications

Vincenzo Taresco; Jiraphong  Suksiriworapong; Ioanna Danai Styliari; Richard Argent; Sadie Swainson; Jonathan Booth; Eleanor Turpin; Charles Laughton; Jonathan Burley; Cameron Alexander; Martin Garnett

doi:10.1039/C6RA21464A

New N-acyl amino acid-functionalized biodegradable polyesters for pharmaceutical and biomedical applications

Vincenzo Taresco
, Jiraphong Suksiriworapong
, Ioanna Danai Styliari
, Richard Argent
, Sadie Swainson
, Jonathan Booth
, Eleanor Turpin
, Charles Laughton
, Jonathan Burley
, Cameron Alexander
, Martin Garnett

Centre for Research into Topical Drug Delivery and Toxicology

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

92 Downloads (Pure)

Abstract

A novel class of biodegradable polyesters has been generated by coupling poly(glycerol adipate) with N-acyl aromatic amino acids. This new set of polymers from this highly versatile polymeric platform may offer unprecedented new opportunities to produce biodegradable and biocompatible polymers with tailorable physical–chemical properties.

Original language	English
Pages (from-to)	109401-109405
Number of pages	5
Journal	RSC Advances
Volume	6
Issue number	111
DOIs	https://doi.org/10.1039/C6RA21464A
Publication status	Published - 9 Nov 2016

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10.1039/C6RA21464ALicence: CC BY

c6ra21464a
© 2016 The Royal Society of Chemistry. This is an open access article published under the Creative Commons Attribution 4.0 International licence (CC BY 4.0 - https://creativecommons.org/licenses/by/4.0/).
Final published version, 820 KBLicence: CC BY

Cite this

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abstract = "A novel class of biodegradable polyesters has been generated by coupling poly(glycerol adipate) with N-acyl aromatic amino acids. This new set of polymers from this highly versatile polymeric platform may offer unprecedented new opportunities to produce biodegradable and biocompatible polymers with tailorable physical–chemical properties.",

author = "Vincenzo Taresco and Jiraphong Suksiriworapong and Styliari, \{Ioanna Danai\} and Richard Argent and Sadie Swainson and Jonathan Booth and Eleanor Turpin and Charles Laughton and Jonathan Burley and Cameron Alexander and Martin Garnett",

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AU - Taresco, Vincenzo

AU - Suksiriworapong, Jiraphong

AU - Styliari, Ioanna Danai

AU - Argent, Richard

AU - Swainson, Sadie

AU - Booth, Jonathan

AU - Turpin, Eleanor

AU - Laughton, Charles

AU - Burley, Jonathan

AU - Alexander, Cameron

AU - Garnett, Martin

N1 - © 2016 The Royal Society of Chemistry. This is an open access article published under the Creative Commons Attribution 4.0 International licence (CC BY 4.0 - https://creativecommons.org/licenses/by/4.0/).

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N2 - A novel class of biodegradable polyesters has been generated by coupling poly(glycerol adipate) with N-acyl aromatic amino acids. This new set of polymers from this highly versatile polymeric platform may offer unprecedented new opportunities to produce biodegradable and biocompatible polymers with tailorable physical–chemical properties.

AB - A novel class of biodegradable polyesters has been generated by coupling poly(glycerol adipate) with N-acyl aromatic amino acids. This new set of polymers from this highly versatile polymeric platform may offer unprecedented new opportunities to produce biodegradable and biocompatible polymers with tailorable physical–chemical properties.

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DO - 10.1039/C6RA21464A

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SP - 109401

EP - 109405

JO - RSC Advances

JF - RSC Advances

IS - 111

ER -

New N-acyl amino acid-functionalized biodegradable polyesters for pharmaceutical and biomedical applications

Abstract

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