Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing

Michael T. Cook, Sarah L. Smith, Vitaliy V. Khutoryanskiy

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)
215 Downloads (Pure)

Abstract

Glycopolymer hydrogels capable of mimicking mucosal tissue in mucoadhesion testing have been designed. Liquid formulations containing mucoadhesive polymers were found to be retained on these tissues to the same extent as ex vivo gastric mucosa, when using a dynamic method of assessing mucoadhesion
Original languageEnglish
Pages (from-to)14447-14450
JournalChemical Communications
Volume51
Early online date21 Jul 2015
DOIs
Publication statusE-pub ahead of print - 21 Jul 2015

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