Obsessive-compulsive disorder

Lior Carmi; Naomi Fineberg; Oded Ben-Arush; Joseph Zohar

Obsessive-compulsive disorder

Lior Carmi, Naomi Fineberg, Oded Ben-Arush, Joseph Zohar

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

Abstract

Introduction: Up to the early 1980s, obsessive–compulsive disorder (OCD) was considered a rare (less than 0.5%) treatment-refractory, chronic condition of psychological origin. Dynamic psychotherapy was widely used and yet had little benefit; this was also the case for pharmacological interventions [1].The observation that clomipramine, a tricyclic drug for depression with a serotonergic profile, is effective in treating symptoms of OCD [2, 3] has increased clinical interest in this disorder, including its epidemiology; several researchers have since reported a prevalence of OCD of about 2% in the general population [4, 5]. However, changes to the diagnostic system, especially the addition of OCD-related disorders (OCRDs) to OCD (and creating the OCRD cluster) [6], have dramatically increased the calculated prevalence of this cluster to close to 9%.

Original language	English
Title of host publication	New Oxford Textbook of Psychiatry
Editors	John Geddes, Nancy Andreasen, Guy Goodwin
Publisher	Oxford University Press (OUP)
Chapter	95
Edition	Third
ISBN (Print)	9780198713005
Publication status	Published - 9 Apr 2020

Cite this

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abstract = "Introduction: Up to the early 1980s, obsessive–compulsive disorder (OCD) was considered a rare (less than 0.5%) treatment-refractory, chronic condition of psychological origin. Dynamic psychotherapy was widely used and yet had little benefit; this was also the case for pharmacological interventions [1].The observation that clomipramine, a tricyclic drug for depression with a serotonergic profile, is effective in treating symptoms of OCD [2, 3] has increased clinical interest in this disorder, including its epidemiology; several researchers have since reported a prevalence of OCD of about 2% in the general population [4, 5]. However, changes to the diagnostic system, especially the addition of OCD-related disorders (OCRDs) to OCD (and creating the OCRD cluster) [6], have dramatically increased the calculated prevalence of this cluster to close to 9%.",

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AU - Fineberg, Naomi

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Obsessive-compulsive disorder

Abstract

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