Optimisation of antihypertensive treatment by crossover rotation of four major classes

Claire Dickerson, A.D. Hingorani, M.J. Ashby, C.R. Palmer, M.J. Brown

Research output: Contribution to journalArticlepeer-review

301 Citations (Scopus)

Abstract

Most comparisons of antihypertensive drugs aee undertaken in parallel groups. We undertook a crossover rotation of the four main classes of antihypertensive drugs, in untreated young hypertensive patients, to assess the response rate with monotherapy achieved by a systematic rotation.
Original languageEnglish
Pages (from-to)2008-2013
JournalLancet
Volume353
Issue number9169
DOIs
Publication statusPublished - 1999

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