Optimisation of antihypertensive treatment by crossover rotation of four major classes

Claire Dickerson, A.D. Hingorani, M.J. Ashby, C.R. Palmer, M.J. Brown

    Research output: Contribution to journalArticlepeer-review

    301 Citations (Scopus)

    Abstract

    Most comparisons of antihypertensive drugs aee undertaken in parallel groups. We undertook a crossover rotation of the four main classes of antihypertensive drugs, in untreated young hypertensive patients, to assess the response rate with monotherapy achieved by a systematic rotation.
    Original languageEnglish
    Pages (from-to)2008-2013
    JournalLancet
    Volume353
    Issue number9169
    DOIs
    Publication statusPublished - 1999

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