Optimisation of antihypertensive treatment by crossover rotation of four major classes

Claire Dickerson; A.D. Hingorani; M.J. Ashby; C.R. Palmer; M.J. Brown

doi:10.1016/S0140-6736(98)07614-4

Optimisation of antihypertensive treatment by crossover rotation of four major classes

Claire Dickerson
, A.D. Hingorani
, M.J. Ashby
, C.R. Palmer
, M.J. Brown

Research output: Contribution to journal › Article › peer-review

335 Citations (Scopus)

Abstract

Most comparisons of antihypertensive drugs aee undertaken in parallel groups. We undertook a crossover rotation of the four main classes of antihypertensive drugs, in untreated young hypertensive patients, to assess the response rate with monotherapy achieved by a systematic rotation.

Original language	English
Pages (from-to)	2008-2013
Journal	Lancet
Volume	353
Issue number	9169
DOIs	https://doi.org/10.1016/S0140-6736(98)07614-4
Publication status	Published - 1999

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title = "Optimisation of antihypertensive treatment by crossover rotation of four major classes",

abstract = "Most comparisons of antihypertensive drugs aee undertaken in parallel groups. We undertook a crossover rotation of the four main classes of antihypertensive drugs, in untreated young hypertensive patients, to assess the response rate with monotherapy achieved by a systematic rotation.",

author = "Claire Dickerson and A.D. Hingorani and M.J. Ashby and C.R. Palmer and M.J. Brown",

note = "Original article can be found at: http://www.sciencedirect.com/science/journal/01406736 Copyright Elsevier Ltd. [Full text of this article is not available in the UHRA]",

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T1 - Optimisation of antihypertensive treatment by crossover rotation of four major classes

AU - Dickerson, Claire

AU - Hingorani, A.D.

AU - Ashby, M.J.

AU - Palmer, C.R.

AU - Brown, M.J.

N1 - Original article can be found at: http://www.sciencedirect.com/science/journal/01406736 Copyright Elsevier Ltd. [Full text of this article is not available in the UHRA]

PY - 1999

Y1 - 1999

N2 - Most comparisons of antihypertensive drugs aee undertaken in parallel groups. We undertook a crossover rotation of the four main classes of antihypertensive drugs, in untreated young hypertensive patients, to assess the response rate with monotherapy achieved by a systematic rotation.

AB - Most comparisons of antihypertensive drugs aee undertaken in parallel groups. We undertook a crossover rotation of the four main classes of antihypertensive drugs, in untreated young hypertensive patients, to assess the response rate with monotherapy achieved by a systematic rotation.

U2 - 10.1016/S0140-6736(98)07614-4

DO - 10.1016/S0140-6736(98)07614-4

M3 - Article

SN - 0140-6736

VL - 353

SP - 2008

EP - 2013

JO - Lancet

JF - Lancet

IS - 9169

ER -

Optimisation of antihypertensive treatment by crossover rotation of four major classes

Abstract

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