Oral Delivery of Hydrophilic Drugs to the Brain

Aikaterini Lalatsa

Oral Delivery of Hydrophilic Drugs to the Brain

Aikaterini Lalatsa (Inventor)

Research output: Patent

Abstract

A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases.

Original language	English
Patent number	WO/2010/100479
IPC	A61K 47/18 (2006.01), A61K 47/36 (2006.01), A61K 47/48 (2006.01)
Publication status	Published - 10 Sept 2010

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title = "Oral Delivery of Hydrophilic Drugs to the Brain",

abstract = "A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases. ",

author = "Aikaterini Lalatsa",

year = "2010",

month = sep,

day = "10",

language = "English",

type = "Patent",

note = "WO/2010/100479; A61K 47/18 (2006.01), A61K 47/36 (2006.01), A61K 47/48 (2006.01)",

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T1 - Oral Delivery of Hydrophilic Drugs to the Brain

AU - Lalatsa, Aikaterini

PY - 2010/9/10

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N2 - A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases.

AB - A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases.

M3 - Patent

M1 - WO/2010/100479

ER -

Oral Delivery of Hydrophilic Drugs to the Brain

Abstract

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