New ALMA CO, HCO+, and 100 GHz continuum observations and Gemini NIFS K-band spectra are combined with previous radio to X-ray data to study Feature i, a highly luminous starburst clump on an outer arm of the interacting galaxy NGC 2207. This clump has an optically-opaque dust cone extending out of its 170 pc core. The measured CO accounts for the dark cone extinction if almost all the gas and dust there is in front of the star clusters. An associated approaching CO outflow has v_z ~ 16 km/s, an estimated molecular mass 8 x 10^6 Msun, and rises to heights ~ 0.9 kpc. A receding CO outflow on the far side with v_z ~ 28 km/s is less extensive. The observed star formation in the core over 10 Myr can supply the dark cone kinetic energy via supernovae and stellar winds. Other signs of intense activity are variable radio continuum suggesting an embedded supernova or other outburst, X-ray emission, and Br-gamma and He I lines with 82 km/s line widths. According to previous models, the retrograde encounter suffered by NGC 2207 caused loss of angular momentum. This compressed its outer disk. We suggest that the resulting inward crashing gas stream hit a massive HI cloud as it was being compressed by a spiral density wave and triggered the observed starburst.