Palladium-mediated annulation of vinyl aziridines with Michael acceptors: stereocontrolled synthesis of substituted pyrrolidines and its application in a formal synthesis of (-)-α-kainic acid

Martin A Lowe; Mehrnoosh Ostovar; Serena Ferrini; C Chun Chen; Paul G Lawrence; Francesco Fontana; Andrew A Calabrese; Varinder K Aggarwal

doi:10.1002/anie.201101389

Palladium-mediated annulation of vinyl aziridines with Michael acceptors: stereocontrolled synthesis of substituted pyrrolidines and its application in a formal synthesis of (-)-α-kainic acid

Martin A Lowe, Mehrnoosh Ostovar, Serena Ferrini, C Chun Chen, Paul G Lawrence, Francesco Fontana, Andrew A Calabrese, Varinder K Aggarwal

Research output: Contribution to journal › Article › peer-review

112 Citations (Scopus)

Original language	English
Pages (from-to)	6370-4
Number of pages	5
Journal	Angewandte Chemie International Edition
Volume	50
Issue number	28
DOIs	https://doi.org/10.1002/anie.201101389
Publication status	Published - 4 Jul 2011

Keywords

Aziridines/chemistry
Butanones/chemistry
Catalysis
Cyclization
Kainic Acid/chemical synthesis
Palladium/chemistry
Pyrrolidines/chemical synthesis
Stereoisomerism

Access to Document

10.1002/anie.201101389

Cite this

Lowe, M. A., Ostovar, M., Ferrini, S., Chen, C. C., Lawrence, P. G., Fontana, F., Calabrese, A. A., & Aggarwal, V. K. (2011). Palladium-mediated annulation of vinyl aziridines with Michael acceptors: stereocontrolled synthesis of substituted pyrrolidines and its application in a formal synthesis of (-)-α-kainic acid. Angewandte Chemie International Edition, 50(28), 6370-4. https://doi.org/10.1002/anie.201101389

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keywords = "Aziridines/chemistry, Butanones/chemistry, Catalysis, Cyclization, Kainic Acid/chemical synthesis, Palladium/chemistry, Pyrrolidines/chemical synthesis, Stereoisomerism",

author = "Lowe, \{Martin A\} and Mehrnoosh Ostovar and Serena Ferrini and Chen, \{C Chun\} and Lawrence, \{Paul G\} and Francesco Fontana and Calabrese, \{Andrew A\} and Aggarwal, \{Varinder K\}",

year = "2011",

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Lowe, MA, Ostovar, M, Ferrini, S, Chen, CC, Lawrence, PG, Fontana, F, Calabrese, AA & Aggarwal, VK 2011, 'Palladium-mediated annulation of vinyl aziridines with Michael acceptors: stereocontrolled synthesis of substituted pyrrolidines and its application in a formal synthesis of (-)-α-kainic acid', Angewandte Chemie International Edition, vol. 50, no. 28, pp. 6370-4. https://doi.org/10.1002/anie.201101389

Palladium-mediated annulation of vinyl aziridines with Michael acceptors: stereocontrolled synthesis of substituted pyrrolidines and its application in a formal synthesis of (-)-α-kainic acid. / Lowe, Martin A; Ostovar, Mehrnoosh; Ferrini, Serena et al.
In: Angewandte Chemie International Edition, Vol. 50, No. 28, 04.07.2011, p. 6370-4.

Research output: Contribution to journal › Article › peer-review

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AU - Chen, C Chun

AU - Lawrence, Paul G

AU - Fontana, Francesco

AU - Calabrese, Andrew A

AU - Aggarwal, Varinder K

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KW - Aziridines/chemistry

KW - Butanones/chemistry

KW - Catalysis

KW - Cyclization

KW - Kainic Acid/chemical synthesis

KW - Palladium/chemistry

KW - Pyrrolidines/chemical synthesis

KW - Stereoisomerism

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