Paresthesia During Naltrexone Treatment: A Case Report

T. Vannucchi, A. Manfredi, A. Vigliotti, F. Schifano, L. Miconi, G. Villani

Research output: Contribution to journalArticlepeer-review


Naltrexone (NTX) is an antagonist of morphine‐like substances; it is orally active and blocks the pharmacological effects of opiates. The authors describe the treatment of a 28‐year‐old woman intravenous heroin user who developed paresthesia of the arms and legs after a standard 50‐mg dose. When the dosage was reduced to 25 mg, this side effect was of shorter duration and finally disappeared after 10 days of dosage at this level. At the 60th day, the dosage was brought back up to 50 mg daily, and no paresthesia was observed. 1995 American Academy of Addiction Psychiatry

Original languageEnglish
Pages (from-to)177-178
Number of pages2
JournalThe American Journal on Addictions
Issue number2
Publication statusPublished - 1 Jan 1995
Externally publishedYes


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