TY - JOUR
T1 - Patient-centred pharmaceutical design to improve acceptability of medicines
T2 - similarities and differences in paediatric and geriatric populations
AU - Liu, Fang
AU - Ranmal, Sejal
AU - Batchelor, Hannah K.
AU - Orlu-Gul, Mine
AU - Ernest, Terry B.
AU - Thomas, Iwan W.
AU - Flanagan, Talia
AU - Tuleu, Catherine
N1 - Open Access. This article is distributed under the terms of the
Creative Commons Attribution Noncommercial License which permits
any noncommercial use, distribution, and reproduction in any
medium, provided the original author(s) and the source are credited.
PY - 2014/10
Y1 - 2014/10
N2 - Patient acceptability of a medicinal product is a key aspect in the development and prescribing of medicines. Children and older adults differ in many aspects from the other age subsets of population and require particular considerations in medication acceptability. This review highlights the similarities and differences in these two age groups in relation to factors affecting acceptability of medicines. New and conventional formulations of medicines are considered regarding their appropriateness for use in children and older people. Aspects of a formulation that impact acceptability in these patient groups are discussed, including, for example, taste/smell/viscosity of a liquid and size/shape of a tablet. A better understanding of the acceptability of existing formulations highlights opportunities for the development of new and more acceptable medicines and facilitates safe and effective prescribing for the young and older populations
AB - Patient acceptability of a medicinal product is a key aspect in the development and prescribing of medicines. Children and older adults differ in many aspects from the other age subsets of population and require particular considerations in medication acceptability. This review highlights the similarities and differences in these two age groups in relation to factors affecting acceptability of medicines. New and conventional formulations of medicines are considered regarding their appropriateness for use in children and older people. Aspects of a formulation that impact acceptability in these patient groups are discussed, including, for example, taste/smell/viscosity of a liquid and size/shape of a tablet. A better understanding of the acceptability of existing formulations highlights opportunities for the development of new and more acceptable medicines and facilitates safe and effective prescribing for the young and older populations
U2 - 10.1007/s40265-014-0265-014-0297-2
DO - 10.1007/s40265-014-0265-014-0297-2
M3 - Literature review
SN - 1179-1950
VL - 74
SP - 1871
EP - 1889
JO - Drugs
JF - Drugs
IS - 16
ER -