Phytochemical Analysis and Antifungal Activity of Extracts from Leaves and Fruit Residues of Brazilian Savanna Plants Aiming Its Use as Safe Fungicides

Caroline Alves Breda, Alessandra Marcon Gasperini, Vera Lucia Garcia, Karin Maia Monteiro, Giovana Anceski Bataglion, Marcos Nogueira Eberlin, Marta Cristina Teixeira Duarte

Research output: Contribution to journalArticlepeer-review

Abstract

Abstract: The increasing demand for safe food without preservatives or pesticides residues has encouraged several studies on natural products with antifungal activity and low toxicity. In this study, ethanolic extracts from leaves and fruit residues (peel and seeds) of three Brazilian savanna species (Acrocomia aculeata, Campomanesia adamantium and Caryocar brasiliense) were evaluated against phytopathogenic fungi. Additionally, the most active extract was chemically characterized by ESI-MS and its oral acute toxicity was evaluated. Extracts from C. brasiliense (pequi) peel and leaves were active against Alternaria alternata, Alternaria solani and Venturia pirina with minimal inhibitory concentrations between 350 and 1000 µg/mL. When incorporated in solid media, these extracts extended the lag phase of A. alternata and A. solani and reduced the growth rate of A. solani. Pequi peel extract showed better antifungal activity and their ESI-MS analysis revealed the presence of substances widely reported as antifungal such as gallic acid, quinic acid, ellagic acid, glucogalin and corilagin. The oral acute toxicity was relatively low, being considered safe for use as a potential natural fungicide. Graphical Abstract: [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)195-204
Number of pages10
JournalNatural Products and Bioprospecting
Volume6
Issue number4
DOIs
Publication statusPublished - 1 Aug 2016
Externally publishedYes

Keywords

  • Brazilian savanna fruits
  • Natural fungicides
  • Phytopathogens
  • Residues

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