TY - JOUR
T1 - Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder
T2 - A report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
AU - Dell'Osso, Bernardo
AU - Benatti, Beatrice
AU - Arici, Chiara
AU - Palazzo, Carlotta
AU - Carlo Altamura, A.
AU - Hollander, Eric
AU - Fineberg, Naomi
AU - Stein, Dan J.
AU - Nicolini, Humberto
AU - Lanzagorta, Nuria
AU - Marazziti, Donatella
AU - Pallanti, Stefano
AU - Van Ameringen, Michael
AU - Lochner, Christine
AU - Karamustafalioglu, Oguz
AU - Hranov, Luchezar
AU - Figee, Martijn
AU - Drummond, Lynne
AU - Rodriguez, Carolyn I.
AU - Grant, John
AU - Denys, Damiaan
AU - Menchon, Jose M.
AU - Zohar, Joseph
N1 - © Cambridge University Press 2017.
PY - 2018/2/1
Y1 - 2018/2/1
N2 - Objective Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. Methods A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson's chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable. Results 14.6% of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17%, p<0.001; particularly tic disorder), medical disorders (51 vs. 15%, p<0.001), and previous hospitalizations (62 vs. 11%, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39%, respectively) compared to North American and Middle-Eastern individuals (13 and 8%, respectively) (‡ 2 =11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables. Conclusions Our international study found a history of SA prevalence of ∼15% in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients.
AB - Objective Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. Methods A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson's chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable. Results 14.6% of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17%, p<0.001; particularly tic disorder), medical disorders (51 vs. 15%, p<0.001), and previous hospitalizations (62 vs. 11%, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39%, respectively) compared to North American and Middle-Eastern individuals (13 and 8%, respectively) (‡ 2 =11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables. Conclusions Our international study found a history of SA prevalence of ∼15% in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients.
KW - comorbidity
KW - hospitalization
KW - Obsessive-compulsive disorder
KW - prevalence
KW - suicide attempt
UR - http://www.scopus.com/inward/record.url?scp=85015622799&partnerID=8YFLogxK
U2 - 10.1017/S1092852917000177
DO - 10.1017/S1092852917000177
M3 - Article
AN - SCOPUS:85015622799
SN - 1092-8529
VL - 23
SP - 59
EP - 66
JO - CNS Spectrums
JF - CNS Spectrums
IS - 1
ER -