Protective mechanism of stabilising excipients against dehydration in the freeze-drying of proteins

Y. Liao; Marc Brown; G.P. Martin

doi:10.1023/A:1021497625645

Protective mechanism of stabilising excipients against dehydration in the freeze-drying of proteins

Y. Liao
, Marc Brown
, G.P. Martin

Research output: Contribution to journal › Article › peer-review

80 Citations (Scopus)

Abstract

To investigate the influence of type and amount of excipient on the preservation of the native structure and the biologic activity of freeze-dried lysozyme and catalase

Original language	English
Pages (from-to)	1854-1861
Journal	Pharmaceutical Research
Volume	19
Issue number	12
DOIs	https://doi.org/10.1023/A:1021497625645
Publication status	Published - 2002

Access to Document

10.1023/A:1021497625645

Cite this

@article{c737310ab18743f99bc9f328bd451bbf,

title = "Protective mechanism of stabilising excipients against dehydration in the freeze-drying of proteins",

abstract = "To investigate the influence of type and amount of excipient on the preservation of the native structure and the biologic activity of freeze-dried lysozyme and catalase",

author = "Y. Liao and Marc Brown and G.P. Martin",

note = "“The original publication is available at www.springerlink.com”. Copyright Springer. [Full text of this article is not available in UHRA]",

year = "2002",

doi = "10.1023/A:1021497625645",

language = "English",

volume = "19",

pages = "1854--1861",

journal = "Pharmaceutical Research",

issn = "0724-8741",

publisher = "Springer Nature ",

number = "12",

}

TY - JOUR

T1 - Protective mechanism of stabilising excipients against dehydration in the freeze-drying of proteins

AU - Liao, Y.

AU - Brown, Marc

AU - Martin, G.P.

N1 - “The original publication is available at www.springerlink.com”. Copyright Springer. [Full text of this article is not available in UHRA]

PY - 2002

Y1 - 2002

N2 - To investigate the influence of type and amount of excipient on the preservation of the native structure and the biologic activity of freeze-dried lysozyme and catalase

AB - To investigate the influence of type and amount of excipient on the preservation of the native structure and the biologic activity of freeze-dried lysozyme and catalase

U2 - 10.1023/A:1021497625645

DO - 10.1023/A:1021497625645

M3 - Article

SN - 0724-8741

VL - 19

SP - 1854

EP - 1861

JO - Pharmaceutical Research

JF - Pharmaceutical Research

IS - 12

ER -

Protective mechanism of stabilising excipients against dehydration in the freeze-drying of proteins

Abstract

Access to Document

Fingerprint

Cite this