Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of post infectious bowel disease.

Weifang Rong; Christopher Keating; B. Sun; L. Dong; David Grundy

doi:10.1111/j.1365-2982.2008.01259.x

Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of post infectious bowel disease.

Weifang Rong
, Christopher Keating
, B. Sun
, L. Dong
, David Grundy

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

Increased sensitivity of the afferent innervation of the gastrointestinal tract reportedly underlies symptoms of discomfort and pain in functional bowel disorders. The present investigation aimed to examine whether the purinergic P2X₂ and P2X₃ receptor subunits contribute to the mechanosensitivity of small intestinal afferents in normal mice and in a murine model of postinfectious gut dysfunction

Original language	English
Pages (from-to)	665-671
Journal	Neurogastroenterology and Motility
Volume	21
Issue number	6
DOIs	https://doi.org/10.1111/j.1365-2982.2008.01259.x
Publication status	Published - Jun 2009

Access to Document

10.1111/j.1365-2982.2008.01259.x

Cite this

@article{d6cb6614fe454f7bafb91c1793964421,

title = "Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of post infectious bowel disease.",

abstract = "Increased sensitivity of the afferent innervation of the gastrointestinal tract reportedly underlies symptoms of discomfort and pain in functional bowel disorders. The present investigation aimed to examine whether the purinergic P2X2 and P2X3 receptor subunits contribute to the mechanosensitivity of small intestinal afferents in normal mice and in a murine model of postinfectious gut dysfunction",

author = "Weifang Rong and Christopher Keating and B. Sun and L. Dong and David Grundy",

year = "2009",

month = jun,

doi = "10.1111/j.1365-2982.2008.01259.x",

language = "English",

volume = "21",

pages = "665--671",

journal = "Neurogastroenterology and Motility",

issn = "1365-2982",

publisher = "Wiley-Blackwell",

number = "6",

}

TY - JOUR

T1 - Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of post infectious bowel disease.

AU - Rong, Weifang

AU - Keating, Christopher

AU - Sun, B.

AU - Dong, L.

AU - Grundy, David

PY - 2009/6

Y1 - 2009/6

N2 - Increased sensitivity of the afferent innervation of the gastrointestinal tract reportedly underlies symptoms of discomfort and pain in functional bowel disorders. The present investigation aimed to examine whether the purinergic P2X2 and P2X3 receptor subunits contribute to the mechanosensitivity of small intestinal afferents in normal mice and in a murine model of postinfectious gut dysfunction

AB - Increased sensitivity of the afferent innervation of the gastrointestinal tract reportedly underlies symptoms of discomfort and pain in functional bowel disorders. The present investigation aimed to examine whether the purinergic P2X2 and P2X3 receptor subunits contribute to the mechanosensitivity of small intestinal afferents in normal mice and in a murine model of postinfectious gut dysfunction

U2 - 10.1111/j.1365-2982.2008.01259.x

DO - 10.1111/j.1365-2982.2008.01259.x

M3 - Article

SN - 1365-2982

VL - 21

SP - 665

EP - 671

JO - Neurogastroenterology and Motility

JF - Neurogastroenterology and Motility

IS - 6

ER -

Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of post infectious bowel disease.

Abstract

Access to Document

Fingerprint

Cite this