Abstract
Aim: To identify HRQoL issues and symptoms in patients with haematological malignancies (HM) and develop a conceptual framework to reflect the inter-relation between them. Methods: A total of 129 patients with HMs were interviewed in a UK multicentre qualitative study. All interviews were audio recorded, transcribed and analysed using NVivo-11. Results: Overall, 34 issues were reported by patients and were grouped into two parts: quality of life (QoL) and symptoms. The most prevalent HRQoL issues were: ‘eating and drinking habits; social life; physical activity; sleep; and psychological well-being’. Furthermore, most prevalent disease-related symptoms were: tiredness; feeling unwell; breathlessness; lack of energy; and back pain. The most prevalent treatment side effects were: ‘tiredness; feeling sick; disturbance in sense of taste; and breathlessness. Conclusions: Both HMs and their treatments have a significant impact on patients’ HRQoL, in particular on issues such as job role change, body image and impact on finances.
| Original language | English |
|---|---|
| Article number | TAH-20-03-015.R1 |
| Journal | Therapeutic Advances in Hematology |
| Publication status | Accepted/In press - 31 Jul 2020 |
Keywords
- Haematological Malignancy, Quality of Life, Symptoms, Clinical Practice, Clinical Research