Reshaping drug development using 3D printing

Atheer Awad; Sarah J. Trenfield; Alvaro Goyanes; Simon Gaisford; Abdul W. Basit

doi:10.1016/j.drudis.2018.05.025

Reshaping drug development using 3D printing

Atheer Awad, Sarah J. Trenfield, Alvaro Goyanes, Simon Gaisford, Abdul W. Basit

School of Life and Medical Sciences

Research output: Contribution to journal › Review article › peer-review

150 Citations (Scopus)

Abstract

The pharmaceutical industry stands on the brink of a revolution, calling for the recognition and embracement of novel techniques. 3D printing (3DP) is forecast to reshape the way in which drugs are designed, manufactured, and used. Although a clear trend towards personalised fabrication is perceived, here we accentuate the merits and shortcomings of each technology, providing insights into aspects such as the efficiency of production, global supply, and logistics. Contemporary opportunities for 3DP in drug discovery and pharmaceutical development and manufacturing are unveiled, offering a forward-looking view on its potential uses as a digitised tool for personalised dispensing of drugs.

Original language	English
Pages (from-to)	1547-1555
Number of pages	9
Journal	Drug Discovery Today
Volume	23
Issue number	8
DOIs	https://doi.org/10.1016/j.drudis.2018.05.025
Publication status	Published - Aug 2018

Access to Document

10.1016/j.drudis.2018.05.025

Cite this

@article{89df06640f3d4092b7f864810bb01da3,

title = "Reshaping drug development using 3D printing",

abstract = "The pharmaceutical industry stands on the brink of a revolution, calling for the recognition and embracement of novel techniques. 3D printing (3DP) is forecast to reshape the way in which drugs are designed, manufactured, and used. Although a clear trend towards personalised fabrication is perceived, here we accentuate the merits and shortcomings of each technology, providing insights into aspects such as the efficiency of production, global supply, and logistics. Contemporary opportunities for 3DP in drug discovery and pharmaceutical development and manufacturing are unveiled, offering a forward-looking view on its potential uses as a digitised tool for personalised dispensing of drugs.",

author = "Atheer Awad and Trenfield, {Sarah J.} and Alvaro Goyanes and Simon Gaisford and Basit, {Abdul W.}",

note = "Funding Information: The authors thank the Engineering and Physical Sciences Research Council (EPSRC) , UK for their partial financial support ( EP/L01646X ). Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",

year = "2018",

month = aug,

doi = "10.1016/j.drudis.2018.05.025",

language = "English",

volume = "23",

pages = "1547--1555",

journal = "Drug Discovery Today",

issn = "1359-6446",

publisher = "Elsevier",

number = "8",

}

TY - JOUR

T1 - Reshaping drug development using 3D printing

AU - Awad, Atheer

AU - Trenfield, Sarah J.

AU - Goyanes, Alvaro

AU - Gaisford, Simon

AU - Basit, Abdul W.

N1 - Funding Information: The authors thank the Engineering and Physical Sciences Research Council (EPSRC) , UK for their partial financial support ( EP/L01646X ). Publisher Copyright: © 2018 Elsevier Ltd

PY - 2018/8

Y1 - 2018/8

N2 - The pharmaceutical industry stands on the brink of a revolution, calling for the recognition and embracement of novel techniques. 3D printing (3DP) is forecast to reshape the way in which drugs are designed, manufactured, and used. Although a clear trend towards personalised fabrication is perceived, here we accentuate the merits and shortcomings of each technology, providing insights into aspects such as the efficiency of production, global supply, and logistics. Contemporary opportunities for 3DP in drug discovery and pharmaceutical development and manufacturing are unveiled, offering a forward-looking view on its potential uses as a digitised tool for personalised dispensing of drugs.

AB - The pharmaceutical industry stands on the brink of a revolution, calling for the recognition and embracement of novel techniques. 3D printing (3DP) is forecast to reshape the way in which drugs are designed, manufactured, and used. Although a clear trend towards personalised fabrication is perceived, here we accentuate the merits and shortcomings of each technology, providing insights into aspects such as the efficiency of production, global supply, and logistics. Contemporary opportunities for 3DP in drug discovery and pharmaceutical development and manufacturing are unveiled, offering a forward-looking view on its potential uses as a digitised tool for personalised dispensing of drugs.

UR - http://www.scopus.com/inward/record.url?scp=85048231796&partnerID=8YFLogxK

U2 - 10.1016/j.drudis.2018.05.025

DO - 10.1016/j.drudis.2018.05.025

M3 - Review article

C2 - 29803932

AN - SCOPUS:85048231796

SN - 1359-6446

VL - 23

SP - 1547

EP - 1555

JO - Drug Discovery Today

JF - Drug Discovery Today

IS - 8

ER -

Reshaping drug development using 3D printing

Abstract

Access to Document

Other files and links

Fingerprint

Cite this