Results of dexamethasone suppression test in early alzheimer dementia

Diego De Leo, Fabrizio Schifano, Guido Magni

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


The frequency of an abnormal response to the Dexamethasone Suppression Test (DST) was examined in 24 non-depressed patients in the early stages of Alzheimer dementia. Results were compared with those obtained in 51 geriatric medical inpatients: 15 with major depression, 18 with dysthymic disorder and 18 normal controls. As an abnormal lack of suppression was found in 9 demented patients, in 9 with major depression, 1 with dysthymic disorder and in 2 the normal controls, it appears that DST alone is not useful in distinguishing dementia, even in its early stages, from major depression. In our experience abnormal DST results in demented patients were unrelated to mood.

Original languageEnglish
Pages (from-to)19-21
Number of pages3
JournalEuropean Archives of Psychiatry and Clinical Neuroscience
Issue number1
Publication statusPublished - 1 Nov 1988
Externally publishedYes


  • Alzheimer dementia
  • Dexamethasone Suppression Test
  • Early stages


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