Abstract
The quadripolar electrodes used for deep brain stimulation are designed to give flexibility in contact configuration, optimize therapeutic effect, and minimize side-effects. A patient with essential tremor did not tolerate a bipolar setting due to the emergence of a pulling sensation in her face. However, when the polarity of the contacts was reversed, a 70% higher voltage was tolerated. Using an electric field model, we predicted that this effect was due to the proximity of the topmost contact to the internal capsule. Post-operative imaging supported this prediction. These results demonstrate how a multi-disciplinary approach allows us to optimize parameter settings.
Original language | English |
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Pages (from-to) | 10-17 |
Number of pages | 8 |
Journal | Neurocase |
Volume | 20 |
Issue number | 1 |
Early online date | 24 Sept 2012 |
DOIs | |
Publication status | Published - 2 Jan 2014 |
Keywords
- Deep Brain Stimulation
- Essential Tremor
- Female
- Humans
- Implantable Neurostimulators
- Middle Aged
- Models, Neurological