TY - JOUR
T1 - Shaping the future
T2 - recent advances of 3D printing in drug delivery and healthcare
AU - Trenfield, Sarah J.
AU - Awad, Atheer
AU - Madla, Christine M.
AU - Hatton, Grace B.
AU - Firth, Jack
AU - Goyanes, Alvaro
AU - Gaisford, Simon
AU - Basit, Abdul W.
N1 - Funding Information:
The work was funded by the Engineering and Physical Sciences Research Council (EPSRC), (EP/L01646X).
Publisher Copyright:
© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2019/10/3
Y1 - 2019/10/3
N2 - Introduction: Three-dimensional (3D) printing is a relatively new, rapid manufacturing technology that has found promising applications in the drug delivery and medical sectors. Arguably, never before has the healthcare industry experienced such a transformative technology. This review aims to discuss the state of the art of 3D printing technology in healthcare and drug delivery. Areas covered: The current and future applications of printing technologies within drug delivery and medicine have been discussed. The latest innovations in 3D printing of customized medical devices, drug-eluting implants, and printlets (3D-printed tablets) with a tailored dose, shape, size, and release characteristics have been covered. The review also covers the state of the art of 3D printing in healthcare (covering topics such as dentistry, surgical and bioprinting of patient-specific organs), as well as the potential of recent innovations, such as 4D printing, to shape the future of drug delivery and to improve treatment pathways for patients. Expert opinion: A future perspective is provided on the potential for 3D printing in healthcare, covering strategies to overcome the major barriers to integration that are faced today.
AB - Introduction: Three-dimensional (3D) printing is a relatively new, rapid manufacturing technology that has found promising applications in the drug delivery and medical sectors. Arguably, never before has the healthcare industry experienced such a transformative technology. This review aims to discuss the state of the art of 3D printing technology in healthcare and drug delivery. Areas covered: The current and future applications of printing technologies within drug delivery and medicine have been discussed. The latest innovations in 3D printing of customized medical devices, drug-eluting implants, and printlets (3D-printed tablets) with a tailored dose, shape, size, and release characteristics have been covered. The review also covers the state of the art of 3D printing in healthcare (covering topics such as dentistry, surgical and bioprinting of patient-specific organs), as well as the potential of recent innovations, such as 4D printing, to shape the future of drug delivery and to improve treatment pathways for patients. Expert opinion: A future perspective is provided on the potential for 3D printing in healthcare, covering strategies to overcome the major barriers to integration that are faced today.
KW - 3D-printed drug products
KW - additive manufacturing
KW - digital healthcare
KW - oral drug delivery systems
KW - personalized pharmaceuticals
KW - Three-dimensional printing
UR - http://www.scopus.com/inward/record.url?scp=85072111793&partnerID=8YFLogxK
U2 - 10.1080/17425247.2019.1660318
DO - 10.1080/17425247.2019.1660318
M3 - Review article
C2 - 31478752
AN - SCOPUS:85072111793
SN - 1742-5247
VL - 16
SP - 1081
EP - 1094
JO - Expert Opinion on Drug Delivery
JF - Expert Opinion on Drug Delivery
IS - 10
ER -