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Should STEMI Patients Receive Opiate Analgesia? The Morphine Paradox
Mohamed Farag
, Nikolaos Spinthakis
, Manivannan Srinivasan
,
Diana Adrienne Gorog
University of Hertfordshire
Department of Clinical, Pharmaceutical and Biological Science
Basic and Clinical Science Unit
Centre for Health Services and Clinical Research
Research output
:
Contribution to journal
›
Review article
›
peer-review
9
Citations (Scopus)
Overview
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Keyphrases
ST-elevation Myocardial Infarction (STEMI)
100%
Morphine
100%
Analgesia
100%
Opiates
100%
Myocardial Infarction Patients
100%
P2Y12 Inhibitors
60%
Clinical Outcomes
40%
Randomized Controlled Trial
20%
Stent Thrombosis
20%
Pain Relief
20%
Presentation Time
20%
Significant Benefit
20%
Clinical High Risk
20%
Negative Impact
20%
Adverse Outcomes
20%
Platelet Reactivity
20%
Reperfusion
20%
Strategies to Overcome
20%
Pharmacokinetic Study
20%
Pharmacodynamic Study
20%
Antiplatelet Activity
20%
Antiplatelet Therapy
20%
Ischemic Events
20%
Opiate Use
20%
Morphine Use
20%
Platelet Aggregation Inhibitors
20%
Infarct Size
20%
Morphine Analgesia
20%
Online Content
20%
Primary Percutaneous Coronary Intervention (pPCI)
20%
Pharmacology, Toxicology and Pharmaceutical Science
Opiate
100%
ST Segment Elevation Myocardial Infarction
100%
Morphine
100%
Purinergic P2Y12 Receptor
42%
Antiplatelet
28%
Pharmacokinetics
14%
Infarction
14%
Antithrombocytic Agent
14%
Pharmacodynamics
14%
Randomized Controlled Trial
14%
Stent Thrombosis
14%
Adverse Outcome
14%