Abstract
The oral route represents the main pathway used to deliver drugs locally and systemically. Despite the technological advancements and rise of novel dosage forms, to date, tablets and capsules still remain the most commonly used types of medications. This is mainly due to the numerous advantages they offer, making them highly preferable over other dosage forms. Indeed, the behavior of a drug product is governed by a multitude of critical quality attributes, which should be carefully considered and defined when designing a formulation. This chapter aims to outline the different types of solid oral dosage forms, give an overview on the manufacturing techniques and excipients involved in their production, as well as discuss the characterization and validation methods recommended during processing.
Original language | English |
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Title of host publication | Remington |
Subtitle of host publication | The Science and Practice of Pharmacy |
Publisher | Elsevier |
Pages | 333-358 |
Number of pages | 26 |
ISBN (Electronic) | 9780128200070 |
DOIs | |
Publication status | Published - 1 Jan 2020 |
Keywords
- 3D printing
- Capsule filling
- Direct compaction
- Excipients
- Granulation
- Modified release
- Oral drug delivery
- Printlets
- Tablet compression
- Tableting