Solid oral dosage forms

Atheer Awad, Sarah J. Trenfield, Abdul W. Basit

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

The oral route represents the main pathway used to deliver drugs locally and systemically. Despite the technological advancements and rise of novel dosage forms, to date, tablets and capsules still remain the most commonly used types of medications. This is mainly due to the numerous advantages they offer, making them highly preferable over other dosage forms. Indeed, the behavior of a drug product is governed by a multitude of critical quality attributes, which should be carefully considered and defined when designing a formulation. This chapter aims to outline the different types of solid oral dosage forms, give an overview on the manufacturing techniques and excipients involved in their production, as well as discuss the characterization and validation methods recommended during processing.

Original languageEnglish
Title of host publicationRemington
Subtitle of host publicationThe Science and Practice of Pharmacy
PublisherElsevier
Pages333-358
Number of pages26
ISBN (Electronic)9780128200070
DOIs
Publication statusPublished - 1 Jan 2020

Keywords

  • 3D printing
  • Capsule filling
  • Direct compaction
  • Excipients
  • Granulation
  • Modified release
  • Oral drug delivery
  • Printlets
  • Tablet compression
  • Tableting

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