Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production

Wendy L. Hall, Katerina Vafeiadou, Jesper Hallund, Susanne Bügel, Corinna Koebnick, Manja Reimann, Marika Ferrari, Francesco Branca, Duncan Talbot, Tony Dadd, Maria Nilsson, Karin Dahlman-Wright, Jan-Ake Gustafsson, Anne-Marie Minihane, Christine M. Williams

Research output: Contribution to journalArticlepeer-review

115 Citations (Scopus)

Abstract

Dietary isoflavones are thought to be cardioprotective because of their structural similarity to estrogen. The reduction of concentrations of circulating inflammatory markers by estrogen may be one of the mechanisms by which premenopausal women are protected against cardiovascular disease.
Original languageEnglish
Pages (from-to)1260-8; quiz 1365-6
JournalAmerican Journal of Clinical Nutrition
Volume82
Issue number6
Publication statusPublished - Dec 2005

Keywords

  • Aged
  • Biological Markers
  • C-Reactive Protein
  • Cardiovascular Diseases
  • Cross-Over Studies
  • Double-Blind Method
  • Equol
  • Estrogen Receptor beta
  • Female
  • Food, Fortified
  • Genotype
  • Humans
  • Isoflavones
  • Middle Aged
  • Phytoestrogens
  • Polymorphism, Single Nucleotide
  • Postmenopause
  • Risk Factors
  • Soy Foods
  • Vascular Cell Adhesion Molecule-1

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