Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells

Kerenza L. Njoh, Laurence H. Patterson, Mire Zloh, Marie Wiltshire, Janet Fisher, Sally Chappell, Simon Ameer-Beg, Yanhong Bai, Daniel Matthews, Rachel J. Errington, Paul J. Smith

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)

Abstract

We report on the potential DNA binding modes and spectral characteristics of the cell-permeant far red fluorescent DNA dye, DRAQ5, in solution and bound within intact cells. Our aim was to determine the constraints for its use in flow cytometry and bioimaging.
Original languageEnglish
Pages (from-to)805-14
Number of pages10
JournalCytometry Part A
Volume69
Issue number8
DOIs
Publication statusPublished - Aug 2006

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