Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5

Adam D. Moorhouse, Christian Spiteri, Pallavi Sharma, Mire Zloh, John E. Moses

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

hLDH-5 has emerged as a promising target for anti-glycolytic cancer chemotherapy. Here we report a first generation of bifunctional inhibitors, which show promising activity against hLDH-5.
Original languageEnglish
Pages (from-to)230-2
Number of pages3
JournalChemical Communications
Volume47
Issue number1
DOIs
Publication statusPublished - 2011

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