TY - JOUR
T1 - Terpenoids from Cameroonian Oxystigma mannii (Baill.) Harms
AU - Siddique, Holly
PY - 2021/3/24
Y1 - 2021/3/24
N2 - We describe two new terpenoids, 3′',5′'-dihydroxycinnamoyl-3β,28,30-dihydroxylup-20(29)-ene (1) and 6S,9S-dihydroxycasbe-3E,7E,11E-trien-5,10-dione (2) and ten known asperglaucide, aridanin, isoscopoletin, maslinic acid, ursolic acid, oleanolic acid, lupeol, sitosterol, stigmasterol and stigmasterol-glucoside from a West African, Guineo-Congolian mangrove and strand forest tree, Oxystigma mannii (Baill.) Harms. The structures of the new compounds were determined based on their 1D and 2D NMR, HRMS and FTIR. DP4+ probabilities were used to assign the configurations for compound 2. The two compounds were tested for their antimicrobial effects against Saccharomyces cerevisiae (BY4743), Escherichia coli (BW25113) and Bacillus subtilis (BY4743), but no inhibition was observed at the maximum concentrations tested (800 μM).
AB - We describe two new terpenoids, 3′',5′'-dihydroxycinnamoyl-3β,28,30-dihydroxylup-20(29)-ene (1) and 6S,9S-dihydroxycasbe-3E,7E,11E-trien-5,10-dione (2) and ten known asperglaucide, aridanin, isoscopoletin, maslinic acid, ursolic acid, oleanolic acid, lupeol, sitosterol, stigmasterol and stigmasterol-glucoside from a West African, Guineo-Congolian mangrove and strand forest tree, Oxystigma mannii (Baill.) Harms. The structures of the new compounds were determined based on their 1D and 2D NMR, HRMS and FTIR. DP4+ probabilities were used to assign the configurations for compound 2. The two compounds were tested for their antimicrobial effects against Saccharomyces cerevisiae (BY4743), Escherichia coli (BW25113) and Bacillus subtilis (BY4743), but no inhibition was observed at the maximum concentrations tested (800 μM).
U2 - 10.1016/j.sciaf.2021.e00751
DO - 10.1016/j.sciaf.2021.e00751
M3 - Article
VL - 12
JO - Scientific African
JF - Scientific African
ER -