TY - JOUR
T1 - The Activity and Polymorphism of the PON1 in Patients with Chronic Liver Disease
T2 - a Systematic Review and Meta-analysis
AU - Salari, Nader
AU - Kazeminia, Mohsen
AU - Mansouri, Kamran
AU - Hosseinian-Far, Amin
AU - Mohammadi, Masoud
N1 - © 2021. Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2021/8/31
Y1 - 2021/8/31
N2 - Background: Liver diseases are among the ten deadliest diseases in the world. Measuring PON1 is a test to assess the degree of liver disorder. There are several preliminary studies on the rate of PON1 activity in people with liver disease, and there are differences between the results of these studies, therefore, the aim of this research work is to determine the level of PON1 activity in people with liver disease using meta-analysis. Method: The study searched to select articles that were published electronically from 2002 to 2020, in national and international databases of SID, MagIran, Embase, ScienceDirect, Scopus, PubMed and Web of Science (WoS). Results: Among the articles included in the meta-analysis, the samples in the case (patients) and control groups were 807 and 2276 respectively. The mean activity of PON1 in individuals with liver disease in the case and control groups were 142.06 ± 7.7 and 272.19 ± 39.6 respectively, and this was statistically significant (P
AB - Background: Liver diseases are among the ten deadliest diseases in the world. Measuring PON1 is a test to assess the degree of liver disorder. There are several preliminary studies on the rate of PON1 activity in people with liver disease, and there are differences between the results of these studies, therefore, the aim of this research work is to determine the level of PON1 activity in people with liver disease using meta-analysis. Method: The study searched to select articles that were published electronically from 2002 to 2020, in national and international databases of SID, MagIran, Embase, ScienceDirect, Scopus, PubMed and Web of Science (WoS). Results: Among the articles included in the meta-analysis, the samples in the case (patients) and control groups were 807 and 2276 respectively. The mean activity of PON1 in individuals with liver disease in the case and control groups were 142.06 ± 7.7 and 272.19 ± 39.6 respectively, and this was statistically significant (P
KW - Liver diseases
KW - Meta-analysis
KW - PON1
U2 - 10.1007/s12029-021-00699-7
DO - 10.1007/s12029-021-00699-7
M3 - Article
SN - 1941-6628
JO - Journal of Gastrointestinal Cancer
JF - Journal of Gastrointestinal Cancer
ER -